描述

Features and Benefits

Disposable Membrane Chromatography units are designed for the rapid selection of appropriate chemistry and method development. The Mustang membrane chromatography starter kit includes both strong anion and cation exchange membrane chromatography Acrodisc units, as well as specific endotoxin removal Acrodisc units. These allow both the rapid selection of the appropriate chemistry for your application, and the opportunity to quickly screen for optimal process parameters to enhance and simplify your process method development.

Starter Kit Contents

Mustang Q Membrane is a strong anion exchanger that effectively binds plasmid DNA, negatively-charged proteins, and viral particles. Typical binding capacities for Acrodisc units with Mustang Q membranes are:

DNA: 3.6 – 4.5 mg/Acrodisc or 20 – 25 mg/mL membrane volume

BSA: 9 – 11 mg/Acrodisc or 50 – 60 mg/mL membrane volume

Mustang SMembrane is a strong cation exchanger that effectively binds positively-charged proteins and viral particles. Typical binding capacities for Acrodisc units with Mustang S membranes are:

Lysozyme 8 – 9 mg/Acrodisc or 45 – 50 mg/mL membrane volume

Mustang E Membrane membranefeatures propriety membrane surface modifications to effectively remove endotoxin from water, saline and buffer solutions.Typical binding capacities for Mustang E membranes are:

Approximately 500,000 EU/Acrodisc unit or approximately 4 x 106 EU/mL membrane volume

Under the following conditions:

0.9% sodium chloride

Minimum challenge level: 10,000 EU/mL

Minimum challenge volume: 60 mL

Endotoxin source: Escherichia coli train 055:B5 (no dispersing agents).

应用

The rapid identification of the correct membrane chemistry for a specific application

Rapid screening of key process parameters

规格

Materials of Construction

Media

Mustang membrane of appropriate chemistry

Housing

Polypropylene

Membrane Bed Volume

Mustang S and Q Membrane

0.18 mL

Mustang E Membrane

0.12 mL

Connections

Inlet

Female Luer-Lok*

Outlet

Male Slip Luer

*Luer-Lok is trademark of Becton-Dickenson & Co.

Operating Pressures

Typical Differential Pressure

< 0.07 bard @ 1 mL/min (< 1.0 psid @ 1 mL/min) Maximum Operating Pressure and Temperature 5.5 bar (80 psi) at 21 – 24 oC 2.1 bar (30 psi) at 60 °C