TDB–Blue Dextrans 蓝色葡聚糖
CAS number: 87915-38-6
Blue dextran 2000 has long been used as a void volume marker in chromatography
and Blue-dextran gel conjugates for chromatography have been available for many
years (e.g. see GE Healthcare Life Sciences; Size Exclusion Chromatography; Princi
ples and Methods). Other important areas of research,
Blue dextran 2000 长期以来一直被用作色谱中的空隙体积标记
和用于色谱的蓝色葡聚糖凝胶偶联物已可用于许多
年（例如，参见 GE Healthcare Life Sciences；尺寸排阻色谱；Princi
ples 和方法）。 其他重要的研究领域，
where blue-dextrans have been used, are:
- Studies on lysosomal activity
- Endothelial cell permeability
- Bovine sperm permeability
- Cornea permeability
- Flow studies in lung
- Cerebro-permeability
- Binding of proteins and enzymes to blue dextran.
使用蓝色葡聚糖的地方是：
溶酶体活性研究
内皮细胞通透性
牛精子通透性
角膜渗透性
肺中的流动研究
脑渗透性
蛋白质和酶与蓝色葡聚糖的结合。
Spectral data: The blue chromophore has an absorbance maximum at 621.5 nm
CAS Number: 87915-38-6
Blue dextrans are synthesised from controlled dextran fractions by reacting with Cibacron blue F3GA. After purification from non-bound dye, products are controlled for molecular weight, solubility, degree of substitution, free dye and loss on drying. TdB Labs offer blue dextran in a wide variety of molecular weights, ranging from 5 kDa to 2000 kDa.
蓝色葡聚糖是通过与 Cibacron blue F3GA 反应从受控的葡聚糖级分合成的。 从非结合染料中纯化后，对产品的分子量、溶解度、取代度、游离染料和干燥失重进行控制。 TdB Labs 提供各种分子量的蓝色葡聚糖，范围从 5 kDa 到 2000 kDa。
Structure
Dextran is a polysaccharide derived from the bacterium Leuconostoc mesenteroides B512F; and consists of an α-D-(1 – 6) linear glucan with a low content (ca. 5%) of side chains linked to 3-carbon of glucose. The dextran is then labelled with Cibacron blue F3GA.
结构
葡聚糖是一种源自肠系膜明串珠菌 B512F 的多糖； 由 α-D-(1 – 6) 线性葡聚糖组成，侧链含量低（约 5%），与葡萄糖的 3-碳相连。 然后用 Cibacron blue F3GA 标记葡聚糖。
Storage and stability
Blue dextrans are stable for more than 6 years when stored dry in well-sealed containers at ambient temperature
储存和稳定性
蓝色葡聚糖在环境温度下干燥储存在密封良好的容器中时可稳定保存 6 年以上
Solubility
Blue dextran dissolves freely in water.
溶解度
蓝色葡聚糖在水中自由溶解。
Applications
Blue dextran has long been used as a void volume marker in chromatography. Blue dextran can also be used as a molecular marker. Read more about application here.
应用
长期以来，蓝色葡聚糖一直被用作色谱中的空隙体积标记。 蓝色葡聚糖也可用作分子标记。 在此处阅读有关应用程序的更多信息。
| Catalog no |
Name |
MW (Da) |
Packsize |
| BD5 |
Blue dextran 5 |
5000 |
1g |
| BD5 |
Blue dextran 5 |
5000 |
10g |
| BD10 |
Blue dextran 10 |
10000 |
1g |
| BD10 |
Blue dextran 10 |
10000 |
10g |
| BD20 |
Blue dextran 20 |
20000 |
1g |
| BD20 |
Blue dextran 20 |
20000 |
10g |
| BD40 |
Blue dextran 40 |
40000 |
1g |
| BD40 |
Blue dextran 40 |
40000 |
10g |
| BD70 |
Blue dextran 70 |
70000 |
1g |
| BD70 |
Blue dextran 70 |
70000 |
10g |
| BD110 |
Blue dextran 110 |
110000 |
1g |
| BD110 |
Blue dextran 110 |
110000 |
10g |
| BD500 |
Blue dextran 500 |
500000 |
1g |
| BD500 |
Blue dextran 500 |
500000 |
10g |
| BD2000 |
Blue dextran 2000 |
2000000 |
1g |
| BD2000 |
Blue dextran 2000 |
2000000 |
10g |
References
Click to view publications
- Beugeling, M. et al. The mechanism behind the biphasic pulsatile drug release from physically mixed poly(dl-lactic(-co-glycolic) acid)-based compacts. International Journal of Pharmaceutics 551, 195–202 (2018).
- Russo, D. et al. Direct photolysis of benzoylecgonine under UV irradiation at 254nm in a continuous flow microcapillary array photoreactor. Chemical Engineering Journal 283, 243–250 (2016).
- Vagenende, V., Ching, T.-J., Chua, R.-J., Jiang, Q. Z. & Gagnon, P. Self-assembly of lipopolysaccharide layers on allantoin crystals. Colloids and Surfaces B: Biointerfaces 120, 8–14 (2014).
