Recombinant Human IL-7

产品编号

JJJP5-10μg
Recombinant Human IL-7
10μg

1671

JJJP5-100μg
Recombinant Human IL-7
100μg

10650

JJJP5-1mg
Recombinant Human IL-7
1mg

34065

Species

Gene ID

Accession

Source

Length

MW

Tag

Human

3574

P13232

E. coli

152aa

17.4kDa

About this protein

Name

Recombinant Human IL-7 (Recombinant Human Interleukin-7; rHuIL-7);重组人白细胞介素7

Synonyms

Lymphopoietin-1; PBGF; IL-7interleukin-7; interleukin 7

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine 2E8 cells is less than 0.5ng/ml, corresponding to a specific activity of >2.0×106IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.

Endotoxin

Less than 1EU/μg of rHuIL-7 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Interleukin-7 (IL-7) is encoded by the IL7 gene and secreted by stromal cells in the red marrow and thymus. It binds to the IL-7 receptor, a heterodimer consisting of IL-7 receptor alpha and IL-2 receptor gamma chain. IL-7 stimulates the differentiation of hematopoietic stem cells into lymphoid progenitor cells and also stimulates proliferation of B cells, T cells and NK cells. Murine IL-7 has approximately 65% amino acid sequence identity with human IL-7 and both proteins exhibit cross-species activity. IL-7 as an immunotherapy agent has been examined in many human clinical trials for various malignancies and during HIV infection.

Amino Acid Sequence

DCDIEGKDGK QYESVLMVSI DQLLDSMKEI GSNCLNNEFN FFKRHICDAN KEGMFLFRAA RKLRQFLKMN STGDFDLHLL KVSEGTTILL NCTGQVKGRK PAALGEAQPT KSLEENKSLK EQKKLNDLCF LKRLLQEIKT CWNKILMGTK EH

包装清单:

产品编号

产品名称

包装

JJJP5-2μg

Recombinant Human IL-7

2μg

JJJP5-10μg

Recombinant Human IL-7

10μg

JJJP5-100μg

Recombinant Human IL-7

100μg

JJJP5-1mg

Recombinant Human IL-7

1mg

说明书

1份

保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

Recombinant Human IL-6

产品编号

JJJP5-5μg
Recombinant Human IL-6
5μg

669

JJJP5-100μg
Recombinant Human IL-6
100μg

6138

JJJP5-1mg
Recombinant Human IL-6
1mg

19650

Species

Gene ID

Accession

Source

Length

MW

Tag

Human

3569

JP0105231

E. coli

183aa

20.7kDa

About this protein

Name

Recombinant Human IL-6 (Recombinant Human Interleukin-6; rHuIL-6);重组人白细胞介素6

Synonyms

BSF-2; IFN-beta 2; MGI-2A; B cell stimulatory factor-2; B-cell differentiation factor; BSF-2; BSF2CTL differentiation factor; CDF; HGFHSFIFNB2Hybridoma growth factor; IFN-beta-2; IL-6B-cell stimulatory factor 2; Interferon beta-2; interleukin 6 (interferon, beta 2); interleukin BSF-2; interleukin-6

Purity

>96% by SDS-PAGE and HPLC analyses.

Biological Activity

Assay #1: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using IL-6-dependent murine 7TD1 cells is less than 0.1ng/ml, corresponding to a specific activity of >1.0×107IU/mg.
Assay #2: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using IL-6-dependent murine T1165 cells is less than 0.8ng/ml, corresponding to a specific activity of >1.25×106IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 1.0EU/μg of rHuIL-6 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Interleukin-6 (IL-6) is an interleukin that in humans is encoded by the IL-6 gene and acts as both a pro-inflammatory and antiinflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response. Furthermore, It plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It also induces myeloma and plasmacytoma growth and induces nerve cells differentiation acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. The human IL-6 is a single non-glycosylated polypeptide chain containing 183 amino acids and it signals through a cell-surface type I cytokine receptor complex consisting of the ligand-binding IL-6Rα chain (CD126), and the signal- transducing component gp130 (also called CD130). The human IL-6 shares about 40%a.a. sequence identity with mouse and rat IL-6 and it is equally active on mouse and rat cells.

Amino Acid Sequence

VPPGEDSKDV AAPHRQPLTS SERIDKQIRY ILDGISALRK ETCNKSNMCE SSKEALAENN LNLPKMAEKD GCFQSGFNEE TCLVKIITGL LEFEVYLEYL QNRFESSEEQ ARAVQMSTKV LIQFLQKKAK NLDAITTPDP TTNASLLTKL QAQNQWLQDM TTHLILRSFK EFLQSSLRAL RQM

包装清单:

产品编号

产品名称

包装

JJJP5-5μg

Recombinant Human IL-6

5μg

JJJP5-20μg

Recombinant Human IL-6

20μg

JJJP5-100μg

Recombinant Human IL-6

100μg

JJJP5-1mg

Recombinant Human IL-6

1mg

说明书

1份

保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

Recombinant Human IL-5

产品编号

JJP53-10μg
Recombinant Human IL-5
10μg

1671

JJP53-100μg
Recombinant Human IL-5
100μg

8800

JJP53-1mg
Recombinant Human IL-5
1mg

28162

Species

Gene ID

Accession

Source

Length

MW

Tag

Human

3567

JP0105113

E. coli

116aa

26.5kDa

About this protein

Name

Recombinant Human IL-5 (Recombinant Human Interleukin-5; rHuIL-5);重组人白细胞介素5

Synonyms

BCDF mu; BCGFII; EDF; Eo-CSF; TRF; B-cell differentiation factor I; EDF; Eosinophil differentiation factor; IL-5T-cell replacing factor; interleukin 5 (colony-stimulating factor, eosinophil); interleukin-5; TRFB cell differentiation factor I

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferationassay using human TF-1 cells is less than 0.1ng/ml, corresponding to a specific activity of >1.0×107IU/mg.

Physical Appearance

Sterile Filtered lyophilized (freeze-dried) liquid-like powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH7.5, 3% trehalose, 0.1% Tween-80.

Endotoxin

Less than 1EU/μg of rHuIL-5 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

The IL-5 gene is located on chromosome 5 in humans, in close proximity to the genes encoding IL-3, IL-4, and granulocytemacrophage colony-stimulating factor (GM-CSF), which are often co-expressed in TH2 cells. Through binding to the IL-5 receptor, IL-5 stimulates B cell growth and increases immunroglobulin secretion. It is also a key mediator in eosinophil activation. Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma. IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely IL-3 and GM-CSF), this glycoprotein in its active form is a homodimer.

Amino Acid Sequence

MIPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES

包装清单:

产品编号

产品名称

包装

JJP53-2μg

Recombinant Human IL-5

2μg

JJP53-10μg

Recombinant Human IL-5

10μg

JJP53-100μg

Recombinant Human IL-5

100μg

JJP53-1mg

Recombinant Human IL-5

1mg

说明书

1份

保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品在冻干时添加了海藻糖作为保护剂,此时冻干后本产品看起来仍然像是液体,属于正常现象。在冻干工艺上,海藻糖作为常用的冻干保护剂,可显著阻止蛋白质二级结构的改变,防止冻干过程中的蛋白变性。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

Recombinant Human IL-4

产品编号

JJJP5-5μg
Recombinant Human IL-4
5μg

669

JJJP5-100μg
Recombinant Human IL-4
100μg

6661

JJJP5-1mg
Recombinant Human IL-4
1mg

21288

Species

Gene ID

Accession

Source

Length

MW

Tag

Human

3565

JP0105112

E. coli

129aa

15kDa

About this protein

Name

Recombinant Human IL-4 (Recombinant Human Interleukin-4; rHuIL-4);重组人白细胞介素4

Synonyms

BCDF; BSF1; B cell growth factor 1; B-cell stimulatory factor 1; BCGF1; BCGF-1; binetrakin; Binetrakin; BSF1; BSF-1; IL-4B_cell stimulatory factor 1; interleukin 4; interleukin-4; Lymphocyte stimulatory factor 1; MGC79402; Pitrakinra; pitrakinra

Purity

>98% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.2ng/ml, corresponding to a specific activity of >5.0×106IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 1EU/μg of rHuIL-4 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Interleukin-4 (IL-4) is a pleiotropic cytokine that induces differentiation of naive helper T cells (Th0 cells) to Th2 cells and produced by mast cells, activated T cells and bone marrow stromal cells. It has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It enhances both secretion and cell surface expression of IgE and IgG1 and also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. The human IL-4 has a compact, globular fold, stabilised by 3 disulphide bonds. The human IL-4 shares about 40%a.a. sequence identity with mouse/rat IL-4 and they are species-specific in their activities.

Amino Acid Sequence

HKCDITLQEI IKTLNSLTEQ KTLCTELTVT DIFAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE NFLERLKTIM REKYSKCSS

包装清单:

产品编号

产品名称

包装

JJJP5-5μg

Recombinant Human IL-4

5μg

JJJP5-20μg

Recombinant Human IL-4

20μg

JJJP5-100μg

Recombinant Human IL-4

100μg

JJJP5-1mg

Recombinant Human IL-4

1mg

说明书

1份

保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

Recombinant Human IL-3

产品编号

JJJP5-10μg
Recombinant Human IL-3
10μg

1671

JJJP5-100μg
Recombinant Human IL-3
100μg

6138

JJJP5-1mg
Recombinant Human IL-3
1mg

19650

Species

Gene ID

Accession

Source

Length

MW

Tag

Human

3562

JP0108700

E. coli

133aa

15kDa

About this protein

Name

Recombinant Human IL-3 (Recombinant Human Interleukin-3; rHuIL-3);重组人白细胞介素3

Synonyms

Hematopoietic growth factor; IL-3MGC79398; interleukin 3 (colony-stimulating factor, multiple); interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGFMGC79399; MULTI-CSF; multilineage-colony-stimulating factor; Multipotential colony-stimulating factor; P-cell stimulating factor; P-cell-stimulating factor

Purity

>96% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1ng/ml, corresponding to a specific activity of >1.0×107IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 1EU/μg of rHuIL-3 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) which is encoded by the IL-3 gene located on chromosome 5 and produced primarily by activated T cells beside human thymic epithelial cells, activated murine mast cells, murine keratinocytes and neurons/astrocytes. The protein acts in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. The human IL-3 reported to be a monomer, as it is known, contains 133 amino acids residues which is a single non-glycosylated polypeptide. Specifically, human and murine IL-3 share low homology and it does not show activity on murine cells.

Amino Acid Sequence

APMTQTTSLK TSWVNCSNMI DEIITHLKQP PLPLLDFNNL NGEDQDILME NNLRRPNLEA FNRAVKSLQN ASAIESILKN LLPCLPLATA APTRHPIHIK DGDWNEFRRK LTFYLKTLEN AQAQQTTLSL AIF

包装清单:

产品编号

产品名称

包装

JJJP5-2μg

Recombinant Human IL-3

2μg

JJJP5-10μg

Recombinant Human IL-3

10μg

JJJP5-100μg

Recombinant Human IL-3

100μg

JJJP5-1mg

Recombinant Human IL-3

1mg

说明书

1份

保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

Recombinant Human IL-2

产品编号

JP515-10μg
Recombinant Human IL-2
10μg

669

JP515-100μg
Recombinant Human IL-2
100μg

1612

JP515-1mg
Recombinant Human IL-2
1mg

5235

Species

Gene ID

Accession

Source

Length

MW

Tag

Human

3558

JJJJP6

E. coli

133aa

15.4kDa

About this protein

Name

Recombinant Human IL-2 (Recombinant Human Interleukin-2; rHuIL-2);重组人白细胞介素2

Synonyms

aldesleukin; Aldesleukin; IL-2lymphokine; interleukin 2; interleukin-2; involved in regulation of T-cell clonal expansion; T cell growth factor; T-cell growth factor; TCGF

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine CTLL-2 cells is less than 0.1ng/ml, corresponding to a specific activity of >1.0×107IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH5.0.

Endotoxin

Less than 1EU/μg of rHuIL-2 as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled H2O to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions. Do not reconstitute in cell culture media directly.

Category

Cytokine

Background

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. The receptor for IL-2 consists of three subunits (55kDa IL-2Rα, 75kDa IL-2Rβ, and 64kDa common gamma chain γc/IL-2Rγ) that are present on the cell surface in varying preformed complexes. Mature human IL-2 shares 56% and 66% amino acid sequence identity with mouse and rat IL-2, respectively. Human and mouse IL-2 exhibit cross-species activity.

Amino Acid Sequence

APTSSSTKKT QLQLEHLLLD LQMILNGINN YKNPKLTRML TFKFYMPKKA TELKHLQCLE EELKPLEEVL NLAQSKNFHL RPRDLISNIN VIVLELKGSE TTFMCEYADE TATIVEFLNR WITFCQSIIS TLT

包装清单:

产品编号

产品名称

包装

JP515-10μg

Recombinant Human IL-2

10μg

JP515-50μg

Recombinant Human IL-2

50μg

JP515-100μg

Recombinant Human IL-2

100μg

JP515-1mg

Recombinant Human IL-2

1mg

说明书

1份

保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

Recombinant Human IL-1 RA

产品编号

JP511-100μg
Recombinant Human IL-1 RA
100μg

2255

JP511-500μg
Recombinant Human IL-1 RA
500μg

3980

JP511-1mg
Recombinant Human IL-1 RA
1mg

Species

Gene ID

Accession

Source

Length

MW

Tag

Human

3557

P18510

E. coli

152aa

17.1kDa

About this Protein

Name

Recombinant Human IL-1 RA (Recombinant Human Interleukin-1 Receptor Antagonist; rHuIL-1RA);重组人白细胞介素1受体拮抗剂

Synonyms

IL-1F3; IL1RN; DIRA; ICIL-1RA; IL1F3; IL1RA; IL-1ra; IL-1ra3; IL1RN; IL-1RN; Interleukin 1 receptor antagonist; IRAP; MVCD4

Purity

>96% by SDS-PAGE and HPLC analyses

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by inhibiting IL-1α-dependent proliferation of murine D10S cells is less than 40ng/ml, corresponding to a specific activity of >2.5×104IU/mg in the presence of 50pg/ml rHuIL-1α.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.

Endotoxin

Less than 1EU/μg of rHuIL-1RA as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Interleukin-1 receptor antagonist (IL-1RA) is a member of the IL-1 family. IL-1RA is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL-1β. This protein inhibits the activities of interleukin 1, alpha (IL-1α) and interleukin 1, beta (IL-1β), and modulates a variety of interleukin 1 related immune and inflammatory responses. IL-4 and IL-13 have been shown to amplify the stimulatory effect of IL1-beta on the production of soluble and intracellular forms of IL1-RA. The regulated expression of IL-1RA in various cell types has been shown to be influenced by cytokines. In synovial fibroblasts the synthesis of IL-1RA is markedly enhanced by IL-1, TNF-α, or PDGF. The protein shows 26% amino acid homology to IL-1β and 19% homology to IL-1α.

Amino Acid Sequence

RPSGRKSSKM QAFRIWDVNQ KTFYLRNNQL VAGYLQGPNV NLEEKIDVVP IEPHALFLGI HGGKMCLSCV KSGDETRLQL EAVNITDLSE NRKQDKRFAF IRSDSGPTTS FESAACPGWF LCTAMEADQP VSLTNMPDEG VMVTKFYFQE DE

包装清单:

产品编号

产品名称

包装

JP511-100μg

Recombinant Human IL-1 RA

100μg

JP511-500μg

Recombinant Human IL-1 RA

500μg

说明书

1份

保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

Recombinant Human IL-1β

产品编号

JJP506-10μg
Recombinant Human IL-1β
10μg

1671

JJP506-100μg
Recombinant Human IL-1β
100μg

7987

JJP506-1mg
Recombinant Human IL-1β
1mg

25545

Species

Gene ID

Accession

Source

Length

MW

Tag

Human

3553

JP1584

E. coli

153aa

17.3kDa

About this protein

Name

Recombinant Human IL-1β (Recombinant Human Interleukin-1β; rHuIL-1β);重组人白细胞介素1β

Synonyms

IL1F2; Interleukin-1 beta; IL-1 beta; Catabolin; IL1B

Purity

>97% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 1.0pg/ml, corresponding to a specific activity of >1.0×109IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH7.4.

Endotoxin

Less than 1EU/μg of rHuIL-1β as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Interleukin-1 beta (IL-1β) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. Both IL-1α and IL-1β binds to the same receptor and has similar but not identical biological properties; The mature human IL-1β shares 96% amino acid sequence identity with rhesus and 67%-78% with canine, mouse and rat IL-1β.

Amino Acid Sequence

APVRSLNCTL RDSQQKSLVM SGPYELKALH LQGQDMEQQV VFSMSFVQGE ESNDKIPVAL GLKEKNLYLS CVLKDDKPTL QLESVDPKNY PKKKMEKRFV FNKIEINNKL EFESAQFPNW YISTSQAENM PVFLGGTKGG QDITDFTMQF VSS

包装清单:

产品编号

产品名称

包装

JJP506-2μg

Recombinant Human IL-1β

2μg

JJP506-10μg

Recombinant Human IL-1β

10μg

JJP506-100μg

Recombinant Human IL-1β

100μg

JJP506-1mg

Recombinant Human IL-1β

1mg

说明书

1份

保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

Recombinant Human IL-1α

产品编号

JJP502-10μg
Recombinant Human IL-1α
10μg

1671

JJP502-100μg
Recombinant Human IL-1α
100μg

7987

JJP502-1mg
Recombinant Human IL-1α
1mg

25545

Species

Gene ID

Accession

Source

Length

MW

Tag

Human

3552

JP1583

E. coli

159aa

18kDa

About this protein

Name

Recombinant Human IL-1α (Recombinant Human Interleukin-1α; rHuIL-1α);重组人白细胞介素1α

Synonyms

IL1A, IL-1F1, Hematopoietin-1, IL1, IL-1 alpha, IL-1A, IL1-ALPHA, IL1F1hematopoietin-1, interleukin-1 alpha, preinterleukin 1 alpha, pro-interleukin-1-alpha

Purity

>97% by SDS-PAGE and HPLC analyses

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine D10S cells is less than 1.0pg/ml, corresponding to a specific activity of >1.0×109IU/mg.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.

Endotoxin

Less than 1EU/μg of rHuIL-1α as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Interleukin-1 alpha (IL-1α) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. Both IL-1α and IL-1β binds to the same receptor and has similar identical biological properties. Among various species, the amino acid sequence of mature IL-1α is conserved 60% to 70% and human IL-1 has been found to be biologically active on murine cell lines. IL-1α recently started to find effective application in cosmetic and dermatological formulations, which allow to significantly harmonizing derma architecture.

Amino Acid Sequence

SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA

包装清单:

产品编号

产品名称

包装

JJP502-2μg

Recombinant Human IL-1α

2μg

JJP502-10μg

Recombinant Human IL-1α

10μg

JJP502-100μg

Recombinant Human IL-1α

100μg

JJP502-1mg

Recombinant Human IL-1α

1mg

说明书

1份

保存条件:
-20℃或更低温度保存,至少一年有效。由于蛋白的每次冻融均会引起部分失活,所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液),须分装后-20℃或更低温度冻存,以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用,溶液中的蛋白很容易粘附在管壁上,并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein,如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点,使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

抗体/试剂/诊断抗体原料,Recombinant human IL-6 protein, C-His

品牌:Bioss/博奥森 | 货号:JP-41177P-100ug

Recombinant human IL-6 protein, C-His

产品编号 JP-41177P
英文名称 Recombinant human IL-6 protein, C-His
中文名称 重组人白介素6蛋白
别    名 IL6; Interleukin BSF 2; B cell differentiation factor; B cell stimulatory factor 2; BSF 2; BSF2; CDF; CTL differentiation factor; Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HGF; HPGF; HSF; Hybridoma growth factor; Hybridoma plasmacytoma growth factor; IFNB2; IL 6; IL6 protein; Interferon beta 2; Interleukin 6 (interferon beta 2); Interleukin 6; IL6_HUMAN; Interleukin6. ;Recombinant human IL-6 protein, C-His  
Specific References  (1)     |     JP-41177P has been referenced in 1 publications.
[IF=4.966] 222Xiaolong Zhang. et al. Baicalein inhibits non‐small‐cell lung cancer invasion and metastasis by reducing ezrin tension in inflammation microenvironment. Cancer Sci. 2020 Oct; 111(10): 3802–3812  other ;  
PubMed:32691974

理论分子量 15kDa
检测分子量 21 kDa
性    状 Lyophilized or Liquid
浓    度 >0.5 mg/ml
物    种 Human
序    列 30-212/212
纯    度 >95% as determined by SDS-PAGE
纯化方法 AC
内毒素 Not analyzed
表达系统 E.coli
活性 Not tested
标签 C-His
缓 冲 液 20 mM Tris-HCl (pH=8.0) with 150 mM NaCl
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. Interleukin 6 is secreted by T cells and macrophages to stimulate immune response, e.g. during infection and after trauma, especially burns or other tissue damage leading to inflammation. IL-6 also plays a role in fighting infection, as IL-6 has been shown in mice to be required for resistance against bacterium Streptococcus pneumoniae.

SWISS:
P05231

Gene ID:
3569

产品图片

本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗,仅可用于科研等非医疗目的。

抗体/试剂/诊断抗体原料,Recombinant mouse IL-6 protein, C-His

品牌:Bioss/博奥森 | 货号:JP-10861P-50ug

Recombinant mouse IL-6 protein, C-His

产品编号 JP-10861P
英文名称 Recombinant mouse IL-6 protein, C-His
中文名称 重组小鼠白介素IL-6蛋白
别    名 IL6; Interleukin BSF 2; B cell differentiation factor; B cell stimulatory factor 2; BSF 2; BSF2; CDF; CTL differentiation factor; Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HGF; HPGF; HSF; Hybridoma growth factor; Hybridoma plasmacytoma growth factor; IFNB2; IL 6; IL6 protein; Interferon beta 2; Interleukin 6 (interferon beta 2); Interleukin 6; IL6_HUMAN; Interleukin6; Recombinant mouse IL-6 protein, C-His  
理论分子量 23kDa
检测分子量 26 kDa
性    状 Lyophilized or Liquid
浓    度 >0.5 mg/ml
物    种 Mouse
序    列 25-211/211
纯    度 >95% as determined by SDS-PAGE
纯化方法 AC
内毒素 Not analyzed
表达系统 E.coli
活性 Not tested
标签 C-His
缓 冲 液 20 mM Tris-HCl with 20% Glycerol
保存条件 Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq, Jun 2011].

SWISS:
P08505

Gene ID:
16193

产品图片

本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗,仅可用于科研等非医疗目的。

抗体/试剂/诊断抗体原料,Recombinant human IL-10 protein (Active, HEK293)

品牌:Bioss/博奥森 | 货号:JP-006-10ug

Recombinant human IL-10 protein (Active, HEK293)

产品编号 JP-006
英文名称 Recombinant human IL-10 protein (Active, HEK293)
中文名称 重组人白介素10 (活性的, Tag free)
别    名 Interleukin-10 precursor; Cytokine synthesis inhibitory factor; CSIF; Cytokine Synthesis Inhibitory Factor; IL 10; IL10A; Interleukin 10; Interleukin10; MGC126450; MGC126451; TGIF; IL10_HUMAN. ;Recombinant human IL-10 protein (Active, HEK293)  人白介素10 重组蛋白; 人白细胞介素10 ; 重组人白介素10; 重组人IL-10;
理论分子量 17kDa
检测分子量 21 kDa
性    状 Lyophilized powder
浓    度 >0.5 mg/ml
物    种 Human
序    列 19-178/178
纯    度 >95% as determined by SDS-PAGE
纯化方法 AC
内毒素 <0.5 EU/μg as determined by LAL.
表达系统 HEK293 cell
活性 Yes
标签 Tag free
缓 冲 液 Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization.
保存条件 Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution.
注意事项 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Interleukin 10(IL-10) is a member of the IL-10 family of α-helical cytokines. IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of a number of proinflammatory cytokines such as IFNgamma, IL-2, IL-3, TNF and GM-CSF. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions.

This recombinant human IL-10 is produced by human cells.(Tag free)

Biological activity:
The activity was measured by its ability to stimulate the proliferation of MC/9-2 cells (mouse master cell line).

Reconstitution:
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.

SWISS:
P18893

Gene ID:
3586

产品图片

本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗,仅可用于科研等非医疗目的。

抗体/试剂/诊断抗体原料,Recombinant human IL-2 protein (Active, HEK293)

品牌:Bioss/博奥森 | 货号:JP-017-10ug

产品编号
JP-017

产品分类
重组蛋白

英文名称
Recombinant human IL-2 protein (Active, HEK293)

中文名称
重组人白介素2 (活性的, Tag free)

英文别名
Interleukin-2; Interleukin 2; Interleukin2; rhIL-2; T-cell growth factor; T Cell Growth Factor; Aldesleukin; IL 2; IL2; Lymphokine; POIL2; T Cell Growth Factor; TCGF; Involved in regulation of T cell clonal expansion; IL2_HUMAN. ;Recombinant human IL-2 protein (Active, HEK293)

中文别名
人白介素2重组蛋白; 重组人白介素2; 人重组白介素2; 重组人白介素2(IL-2);

蛋白细胞定位
分泌型蛋白

纯化方法
AC

理论分子量
15kDa

检测分子量
17 kDa

GeneID
3558

Swiss
P60568

浓度
>0.5 mg/ml

储存液
Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization.

保存条件
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution.

Subunit

Subcellular Location
Secreted.

DISEASE
Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.

Similarity
Belongs to the IL-2 family.

Database links

Entrez Gene: 3558 Human

Entrez Gene: 16183 Mouse

Entrez Gene: 116562 Rat

Omim: 147680 Human

SwissProt: P60568 Human

SwissProt: P04351 Mouse

SwissProt: P17108 Rat

Unigene: 89679 Human

Unigene: 14190 Mouse

Unigene: 9871 Rat

背景资料
The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]

多肽活性
Yes

蛋白质与多肽-多肽序列
21-153/153

小分子偶联蛋白-蛋白载体

标签
Tag free

纯度
>95% as determined by SDS-PAGE

内毒素
<0.5 EU/μg as determined by LAL.

重组蛋白-表达系统

HEK293 cell

复溶
Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗,仅可用于科研等非医疗目的。

炎症性疾病&代谢综合征生物标记 ELISA试剂盒

产品中心 > 生命科学 > 疾病研究 > 代谢&糖尿病&肥胖症

炎症性疾病&代谢综合征生物标记 ELISA试剂盒

  • 产品特性
  • 相关资料
  • Q&A
  • 参考文献

炎症性疾病&代谢综合征生物标记 ELISA试剂盒

炎症性疾病&代谢综合征生物标记 ELISA试剂盒


来自AbfrontierCymax™ 细胞因子ELISA试剂盒

来自JaICA氧化应激测定

 


◆IL-37 ELISA试剂盒 独特性!

一种新型抗炎性IL-1家族成员

  IL-1家族成员——IL-37是对哮喘、肠道炎症SLE发病机理皮肤炎症肥胖患者的胰岛素抵抗和心血管疾病等疾病具有调节功能的抗炎细胞因子。


REVIEWS:The Role of IL-37 in Non-Cancerous Diseases: V.A Ding, et al.; Pathol. Oncol. Res. 23, 463 (2017)

REVIEWS:Role of Anti-inflammatory Cytokines IL-35 and IL-37 in Asthma: D. Hu; Inflammation 40, 697 (2017)

REVIEWS:A protective role of IL-37 in cancer: a new hope for cancer patients: A. Abulkhir, et al.; J. Leukoc. Biol. 101, 395 (2017)

REVIEWS:The emerging role of interleukin-37 in cardiovascular diseases: X. Zhuang, et al.; Immun. Inflamm. Dis.  (Epub ahead of 

                   print) (2017)

REVIEWS:Homodimerization attenuatesthe anti-inflammatory activity of interleukin-37: A.M. Ellisdon, et al.; Sci. Immunol. 2, eaaj1548

                   (2017)

产品编号

产品名称

包装

AG-45A-0041YEK-KI01

白介素-37(人)ELISA 试剂盒

IL-37 (human) ELISA Kit

96 wells

AG-45A-0041YTP-KI01

96 wells×2

AG-45A-0041YPP-KI01

96 wells×2

AG-45A-0041Y规格


  本实验已证明该测定法可检测天然重组单体和二聚体人IL-37。


炎症性疾病&代谢综合征生物标记 ELISA试剂盒

灵敏度:10 pg/mL

范围:16~1000 pg/mL

样品:血清、血浆Manual IL-37 (human) ELISA Kit

◆Nampt / Visfatin ELISA试剂盒 标准!


代谢综合征炎症状态的生物标记物


  烟酰胺磷酸核糖转移酶(Nampt; pre-B细胞集落增强因子; PBEF; Visfatin)是由脂肪组织分泌并参与烟酰胺腺嘌呤二核苷酸(NAD+)生物合成的脂肪因子。有证明指出,在不同的疾病如糖尿病、肥胖症、动脉粥样硬化、胎儿生长迟缓、败血症、炎症性肠病(IBD)、克罗恩病、类风湿性关节炎、先兆子痫和各种癌症中,Nampt表达增强。


REVIEWS:Nampt and its potential role in inflammation and type 2 diabetes: A. Garten, et al.; Handb.Exp. Pharmacol. 203 ,147 (2011)

REVIEWS:Adipose tissue dysfunction and inflammation in cardiovascular disease: N. Wronkowitz, et al.; Front. Horm. Res. 43, 79 

                  (2014)

REVIEWS:The role of visfatin (PBEF/Nampt) in pregnancy complications: T. Pavlova, et al.; J. Reprod. Immunol.112, 102 (2015)

REVIEWS:New markers of insulin resistance in polycystic ovary syndrome: K. Polak, et al.; J. Endocrinol. Invest. 40,1 (2017)

 

产品编号

产品名称

规格

AG-45A-0006YEK-KI01

Nampt (内脂素/PBEF)(人) ELISA 试剂盒

Nampt (Visfatin/PBEF) (human) ELISA Kit

96 wells

AG-45A-0006YTP-KI01

Nampt(内脂素/PBEF)(人) ELISA 试剂盒(2盒)

Nampt (Visfatin/PBEF) (human) ELISA Kit (Twin Plex)

96 wells×2

AG-45A-0006YPP-KI01

Nampt(内脂素/PBEF)(人) ELISA 试剂盒 (5盒)

Nampt (Visfatin/PBEF) (human) ELISA Kit (Penta Plex)

96 wells×5

AG-45A-0008YEK-KI01

NAMPT(内脂素/   PBEF)(人)(胞内)ELISA试剂盒

Nampt (Visfatin/PBEF) (human) (IntraCellular) ELISA Kit

96 wells

AG-45A-0008YTP-KI01

NAMPT(内脂素/PBEF)(人)(胞内)ELISA试剂盒(2盒)

Nampt (Visfatin/PBEF) (human) (IntraCellular) ELISA Kit (Twin Plex)

96 wells×2

AG-45A-0007YEK-KI01

Nampt(内脂素/PBEF)(小鼠/大鼠) 双 ELISA 试剂盒

Nampt (Visfatin/PBEF) (mouse/rat) Dual ELISA Kit

96 wells×2

AG-45A-0007YTP-KI01

Nampt(内脂素/PBEF)(小鼠/大鼠) 双 ELISA 试剂盒(2盒)

Nampt (Visfatin/PBEF) (mouse/rat) Dual ELISA Kit (Twin Plex)

96 wells×2

AG-45A-0006Y规格


  检测天然和重组人Nampt。


炎症性疾病&代谢综合征生物标记 ELISA试剂盒

灵敏度:30 pg/mL

范围:125~8000 pg/mL

样品:血清

◆Irisin ELISA试剂盒 标准!


能量代谢生物标记


  Irisin是由小鼠和人类骨骼肌分泌的运动激素。 Irisin通过增加能量消耗来改善全身新陈代谢。循环虹膜水平在急性运动后会上调,且与能量代谢、肥胖、2型糖尿病(T2D)、胰岛素抵抗和慢性阻塞性肺疾病(COPD)有关。


REVIEWS:LIT:Irisin, a novel myokine is an independent predictor for sarcopenia and carotid atherosclerosis in dialysis patients: M.J.  

REVIEWS:Lee,et al.; Atheroscler. 242, 476 (2015)

REVIEWS:Chronic CNS oxytocin signaling preferentially induces fat loss in highfat diet-fed rats by enhancing satiety responses and 

REVIEWS:increasing lipid utilization: J.E. Blevins, et al.; Am. J. Physiol. 310, R640 (2016)

REVIEWS:Eicosapentaenoic acid regulates brown adipose tissue metabolism in high-fat-fed mice and in clonal brown adipocytes: 

REVIEWS:M. Pahlavanni, et al.; J. Nutr. Biochem.39, 101 (2017)

 

产品编号

产品名称

包装

AG-45A-0046YEK-KI01

新型瘦素竞争ELISA 试剂盒

Irisin Competitive ELISA Kit

96 wells

AG-45A-0046YTP-KI01

新型瘦素竞争 ELISA 试剂盒 (2盒)

Irisin Competitive ELISA Kit (Twin Plex)

96 wells×2

AG-45A-0046YPP-KI01

新型瘦素竞争ELISA 试剂盒 (5盒)

Irisin Competitive ELISA Kit (Penta Plex)

96 wells×5

 

AG-45A-0046Y规格

  检测天然和重组人类虹膜蛋白。 基于100%序列同一性,也可在小鼠、大鼠和猴等生物样品中起作用。 不与FNDC4交叉反应。


炎症性疾病&代谢综合征生物标记 ELISA试剂盒

灵敏度:1 ng/mL

范围:0.001~5 μg/mL

样品:血清,血浆,细胞培养上清液

 

◆锌-α-2-糖蛋白的ELISA试剂盒 Turbo ELISA™


脓毒症代谢综合征生物标记物


  ZAG以脂肪因子的形式主要在白色脂肪库和小鼠的肩胛内棕色脂肪中表达。它可能通过对脂联素产生的影响来参与调节肥胖和代谢。 ZAG在糖尿病患者的尿液中含量上调,据报道与癌症和代谢综合征等多种疾病有关。最近,有证明指出血清中的ZAG水平在急性脓毒症中减少并且在临床恢复期间上升。


REVIEWS:Zinc alpha 2-glycoprotein: a multidisciplinary protein: M.I. Hassan, et al.; Mol. Cancer Res. 6, 892 (2008)

REVIEWS:Zinc-α2-glycoprotein: an adipokine modulator of body fat mass? C. Bing, et al.; Int. J. Obes. (Lond).34, 1559 (2010)

REVIEWS:Zinc-α2-glycoprotein as a marker of fat catabolism in humans: A. Cabassi& S. Tedeschi; Curr. 

REVIEWS:Opin.Clin. Nutr.Metab. Care 16, 267 (2013)

 

产品编号

产品名称

包装

AG-48B-1000-KI01

锌 – α-2-糖蛋白(人)Turbo ELISA™ 试剂盒

Zinc-alpha-2-glycoprotein (human) TurboELISA™ Kit

1 kit

AG-46B-0008-KI01

锌-alpha-2糖蛋白检测套装

Zinc-alpha-2-glycoprotein (human) Matched Pair Detection Set

1 set

 

AG-48B-1000的规格


  检测天然和重组人锌-α-2-糖蛋白。不可检测小鼠锌-α-2-糖蛋白。

  该检测方法是耗时小于1小时,用于定量检测生物体液中人ZAG的夹心Elisa法。


炎症性疾病&代谢综合征生物标记 ELISA试剂盒

灵敏度:0.23 ng/mL

范围:0.9375~60 ng/mL

样品:血清、血浆细胞培养上清液


  另外提供:元素分析:Ca,Cu,Fe,Mg,Zn,UIBC


免责声明

1. 本公司密切关注本网站发布的内容,但不保证发布内容的准确性、完整性、可靠性和最新性等。

2. 本公司不保证使用本网站期间不会出现故障或计算机病毒污染的风险。

3. 无论何种原因,使用本网站时给用户或第三方造成的任何不利或损害,本公司概不负责。此外,对于用户与其他用户或第三方之间因本网站发生的任何交易、通讯

3. 纠纷,本公司概不负责。

4. 本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗,仅可用于科研等非医疗目的。如任何用户将本网站提供的产品和服务用临床诊断或治

4. 疗,以及他特定的用途或行为,本公司概不保证其安全性和有效性,并且不负任何相关的法律责任。

牛皮癣的生物标记物IL-36γ(人)ELISA试剂盒

产品中心 > 生命科学 > 疾病研究 > 感染&自身免疫疾病

牛皮癣的生物标记物IL-36γ(人)ELISA试剂盒

  • 产品特性
  • 相关资料
  • Q&A
  • 参考文献

牛皮癣的生物标记物IL-36γ(人)ELISA试剂盒IL-36γ(人)ELISA 试剂盒

 



◆产品描述


别名:白细胞介素-1家族成员9;IL-1F9

产品类型:试剂盒



特性


应用类别:ELISA 定量试剂盒

特异性:检测天然和重组人 IL-36γ。

交叉反应性:

数量:1 × 96 孔

灵敏度:3 pg/mL

检测范围:3.9-250 pg/mL

样品类型:细胞培养上清液,血清

检测方式:夹心法

测定方式:比色法

 


◆运输和保存


运输:干冰

短期储存:4℃

长期储存:4℃

保存建议:标准品复溶后,分装保存在-20°C。避免反复冻融。

     使用前将微孔板和试剂恢复至室温。

使用/稳定性: 在生产后1年内使用。具体信息参考 ELISA 试剂盒上的有效期限。

 


◆产品描述


  IL-36α(IL-1F6)、IL-36β(IL-1F8)和 IL-36γ(IL-1F9)是 IL-1细胞因子家族的成员,其与 IL-36R(IL-1Rrp2)和 IL-1RAcP 结合 ,激活与 IL-1 类似的细胞内信号,并被 IL-36Ra 抑制。 IL-36 的表达主要在肺和皮肤中,可以来源于不同的上皮细胞类型,包括角质形成细胞,支气管上皮细胞以及巨噬细胞,单核细胞和不同的T细胞亚群。 IL-36 家族成员诱导促炎性细胞因子 IL-12、IL-1β、IL-6、TNF-α 和 IL-23的产生,从而促进中性粒细胞内流、树突细胞(DC)活化,1型T辅助细胞(Th1)极化和产生 IL-17 的T细胞(αβT细胞和 γδT细胞)和角质形成细胞的增殖。IL-36γ 诱导巨噬细胞对结核杆菌感染及其释放的抗菌肽的作用已被提出。在各种哮喘模型中 IL-36γ 在肺中也被诱导,并且可由支气管上皮细胞产生以作用于病毒感染,吸烟或炎性细胞因子,并在哮喘性肺炎中起重要作用。 IL-36γ 可能是肠道炎症性疾病的一个潜在的生物标志物, 在银屑病患者的炎症皮肤和过敏性接触性皮炎中高度表达。 IL-36γ 血清水平提高与银屑病严重程度和对用抗 TNF 治疗的应答相关。



◆产品列表


产品编号

产品名称

包装

AG-45B-0008-KI01

IL-36γ(human) ELISA Kit

白细胞介素 36γ(人)ELISA 试剂盒

1×96 wells

 


免责声明

1. 本公司密切关注本网站发布的内容,但不保证发布内容的准确性、完整性、可靠性和最新性等。

2. 本公司不保证使用本网站期间不会出现故障或计算机病毒污染的风险。

3. 无论何种原因,使用本网站时给用户或第三方造成的任何不利或损害,本公司概不负责。此外,对于用户与其他用户或第三方之间因本网站发生的任何交易、通讯

3. 纠纷,本公司概不负责。

4. 本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗,仅可用于科研等非医疗目的。如任何用户将本网站提供的产品和服务用临床诊断或治

4. 疗,以及他特定的用途或行为,本公司概不保证其安全性和有效性,并且不负任何相关的法律责任。

IL-33 (人), ELISA 试剂盒 IL-33 (human), ELISA kit

产品中心 > 生命科学 > 疾病研究 > 感染&自身免疫疾病

IL-33 (人), ELISA 试剂盒
IL-33 (human), ELISA kit

  • 产品特性
  • 相关资料
  • Q&A
  • 参考文献

IL-33(释放于坏死细胞)动员杀伤性T细胞应对病毒感染IL-33 (人), ELISA 试剂盒                              IL-33 (human), ELISA kit

 


 

原理

  细胞死亡后会释放一类特殊的蛋白质 Alarmin(暂译为警报素),通过检测 Alarmin 可识别组织创伤。然而在抗病毒免疫系统中,Alarmin 所起的作用不是很明确。最近瑞士日内瓦大学和德国柏林夏里特医科大学研究人员发现在脾脏和淋巴结中病毒的复制可导致受感染的细胞死亡。这些坏死的细胞可释放出 Alarmin,其中主要的是白介素-33(IL-33),它可通过 ST2 受体激活 CD8+ T(CTLs)细胞,对病毒感染作出反应。研究发现缺乏 IL-33 的小鼠,CTL 对病毒感染的免疫反应也较低。此项研究具有里程碑意义,因为提出了一个新的免疫机制:坏死细胞会释放出 Alarmin 动员杀伤性T细胞应对感染,在未来对抗艾滋、丙型肝炎而开发新的疫苗,对于癌症治疗有重要作用。

  Enzo Life Sciences 提供大量细胞坏死研究用产品,先天性免疫适应性免疫等。许多与 Alarmin IL-33 有关,供科研人员选择。

◆优点特色

 

 产品名称

 特点

 IL-33 (human), ELISA kit

 Reliably measure as little as 1.7 pg/mL of IL-33

 IL-33 (mouse) ELISA Kit

 Reliably measure as little as 10pg/mL of IL-33

 IL-33 soluble (human), detection   set

 Reliably measure as little as 5pg/mL of IL-33

 GFP-Certified™ Apoptosis/Necrosis  detection   kit

 Cell-based assay for microscopy and flow   cytometry

 IL-33 (human), (recombinant)

 ≥95% pure (SDS-PAGE)

 IL-33 (human), (recombinant)

 ≥95% pure (SDS-PAGE), FLAG-tag

 IL-33 (human), (recombinant)

 ≥95% pure (SDS-PAGE), His-tag

 Pro-IL-33 (human), (recombinant)

 ≥90% pure (SDS-PAGE), His-tag

 IL-33 (human) (homeodomain-like   helix-turn-helix), (recombinant)

 Human IL-33 homeodomain, fused at C-   terminus to His-tag, ≥95% pure (SDS-PAGE)

 IL-33 (mouse), (recombinant)

 ≥95% pure (SDS-PAGE)

 IL-33 (mouse), (recombinant)

 ≥95% pure (SDS-PAGE), His-tag

 IL-33 (rat), (recombinant)

 ≥95% pure (SDS-PAGE)

 IL-33 (human), mAb

 Suitable for ELISA, IHC, IP, WB (clone     IL33305B)

 IL-33 (human), pAb

 Suitable for ELISA, WB

 IL-33 (human), pAb

 Suitable for ELISA, WB, Biotin conjugate

 IL-33 (mouse), pAb

 Suitable for ELISA, WB

 IL-33, mAb

 Recognizes human and mouse IL-33. ELISA,  IP, 

 WB.(clone IL33026B)

 IL-33, mAb

 Recognizes human IL-33. Weakly cross-reacts 

 with mouse IL-33. ELISA, WB. (clone IL33068A)

 IL-33, mAb

 Recognizes human, mouse and rat pro-IL-33 

 (precursor) and mature IL-33. ELISA, IHC, IHC, 

 IP, WB   (clone Nessy-1)

 IL-33, mAb

 Biotin-conjugate (clone Nessy-1)

 IL-33, mAb

 Preservative free, (clone Nessy-1)

 IL-33, mAb

 ICC, WB (clone Nessy-2)

 IL-33, pAb (AT110)

 Recognizes human, mouse and rat pro-IL-33 

 and mature IL-33, ELISA, WB

 IL-33, pAb (AT110)

 Biotin-conjugate

 ST2 (human), (recombinant)

 ≥90% pure (SDS-PAGE)

 ST2 (human), mAb

 ELISA, IHC, IHC, WB (clone ST33868)

 ST2 (human):Fc (human), (recombinant)

 ≥90% pure (SDS-PAGE)

 ST2 (mouse):Fc (human), (recombinant)

 ≥95% pure (SDS-PAGE)

 IL-1RAcP (human):Fc (human) (recombinant)

 Forms heterodimer complex with ST2 to make 

 the IL-33 receptor. ≥95% pure (SDS-PAGE)

 


产品列表

产品编号 产品名称 产品规格 产品等级 备注
ADI-900-201 IL-33 (human), ELISA kit
 IL-33 (人), ELISA试剂盒
96wells等

免责声明

1. 本公司密切关注本网站发布的内容,但不保证发布内容的准确性、完整性、可靠性和最新性等。

2. 本公司不保证使用本网站期间不会出现故障或计算机病毒污染的风险。

3. 无论何种原因,使用本网站时给用户或第三方造成的任何不利或损害,本公司概不负责。此外,对于用户与其他用户或第三方之间因本网站发生的任何交易、通讯

3. 纠纷,本公司概不负责。

4. 本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗,仅可用于科研等非医疗目的。如任何用户将本网站提供的产品和服务用临床诊断或治

4. 疗,以及他特定的用途或行为,本公司概不保证其安全性和有效性,并且不负任何相关的法律责任。

增加3种产品! 可检测血清血浆样本 LBIS® 试剂盒

产品中心 > 生命科学 > 疾病研究 > 代谢&糖尿病&肥胖症

增加3种产品! 可检测血清血浆样本 LBIS® 试剂盒

  • 产品特性
  • 相关资料
  • Q&A
  • 参考文献

增加3种产品! 可检测血清血浆样本 LBIS® 试剂盒增加3种产品!

正常血清/血浆样本也可检测

LBIS® 系列



◆LBIS® Human IL-6 ELISA Kit


  IL-6 是 189 个氨基酸的分泌性糖蛋白,是促进B细胞分化成抗体生成细胞的细胞因子。有研究表示 ,IL-6 与类风湿关节炎的病情有关,其作用在类风湿关节炎等自身免疫性疾病、炎症性疾病领域受到关注。

  本试剂盒能短时间,高灵敏度检测人血清(血浆)中的微量 IL-6。

产品概要

● 标准曲线范围:1.16~500 pg/mL

● 检测时间:总反应时间 3 小时 50 分

● 样本量:100 μL

● 测定波长:主波长 450 nm /副波长 620 nm

● 样本:人血清/血浆(肝素/EDTA)

增加3种产品! 可检测血清血浆样本 LBIS® 试剂盒


〈标准曲线〉

增加3种产品! 可检测血清血浆样本 LBIS® 试剂盒

 


◆LBIS® Human IL-8(CXCL8)ELISA Kit


  IL-8 是通过炎症性细胞因子的刺激在成纤维细胞或单核细胞、血管内皮细胞中产生的 72 或 77 个氨基酸的 2 种类型的炎症性 CXC 趋化因子。IL-8 与多种疾病的相关,并在类风湿关节炎、哮喘等呼吸道疾病、痛风、牙周炎、癌症等研究领域受到了关注。

  本试剂盒能短时间,高灵敏度检测人血清(血浆)中的微量 IL-8。

产品概要

● 标准曲线范围:0.686~500 pg/mL

● 检测时间:总反应时间 3 小时 50 分

● 样本量:100 μL

● 测定波长:主波长 450 nm / 副波长 620 nm

● 样本:人血清/血浆(肝素/EDTA)


〈标准曲线〉

增加3种产品! 可检测血清血浆样本 LBIS® 试剂盒

 


◆LBIS® Human TNF-α ELISA Kit


  TNF-α 是能引起移植到小鼠中的肿瘤发生出血性坏死的诱导因子,是由 157 个氨基酸组成的炎症性细胞因子。TNF-α 与多种疾病相关,在类风湿关节炎、炎症、糖尿病・高血脂、肾病、白血病、骨质疏松等领域受到关注。

  本试剂盒能短时间,高灵敏度检测人血清(血浆)中的微量 TNF-α。


产品概要

● 标准曲线范围:2.05~500 pg/mL

● 检测时间:总反应时间 3 小时 50 分

● 样本量:100 μL

● 测定波长:主波长 450 nm / 副波长 620 nm

● 样本:人血清/血浆(肝素/EDTA)


〈标准曲线〉

增加3种产品! 可检测血清血浆样本 LBIS® 试剂盒



欲了解相关信息请点击文字:

新产品 人IL-6/IL-8/TNF-α ELISA试剂盒发售通知

Lbis® 疾病相关动物模型ELISA试剂盒系列


产品列表

产品编号 产品名称 产品规格 产品等级 备注
635-42311 人IL-6 ELISA试剂盒,AKH-IL6
LBIS®  Human IL-6 ELISA Kit
96次
632-42321 人IL-8(CXCL8) ELISA试剂盒,AKH-IL8
LBIS®  Human IL-8(CXCL8) ELISA Kit
96次
639-42331 人 TNF-α ELISA试剂盒,AKH-TNFA
LBIS®  Human TNF-α ELISA Kit
96次

免责声明

1. 本公司密切关注本网站发布的内容,但不保证发布内容的准确性、完整性、可靠性和最新性等。

2. 本公司不保证使用本网站期间不会出现故障或计算机病毒污染的风险。

3. 无论何种原因,使用本网站时给用户或第三方造成的任何不利或损害,本公司概不负责。此外,对于用户与其他用户或第三方之间因本网站发生的任何交易、通讯

3. 纠纷,本公司概不负责。

4. 本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗,仅可用于科研等非医疗目的。如任何用户将本网站提供的产品和服务用临床诊断或治

4. 疗,以及他特定的用途或行为,本公司概不保证其安全性和有效性,并且不负任何相关的法律责任。

IL-2 (人) Superkine H9T (单体):Fc-KIH (人),重组,HEK 293细

AdipoGen Life Sciences专注于从哺乳动物细胞中生产具有增强活性和稳定性的重组蛋白。通过采用专有的内部技术以及成熟且公开的技术,为细胞治疗研究等不同研究领域设计、开发与生产创新重组蛋白。

与 Fc 结合的单体蛋白(KIH技术)

AdipoGen Life Sciences利用knobs-into-holes(KIH)技术将各种白细胞介素(如IL-2、IL-37和IL-38)与Fc融合蛋白结合。最终的KIH蛋白为单体蛋白,可极大地增强稳定性并改善药代动力学(PK),同时保持细胞因子活性。

产品速递

产品编号

产品名称

来源

规格

AG-40B-0223

IL-2 (human) Superkine H9T   (monomeric):Fc-KIH (human)(rec.)
IL-2 (人) Superkine H9T (单体):Fc-KIH (人) (重组)

HEK 293细胞

3 x 10 μg

10 μg

100 μg

AG-40B-0224

IL-2 (human) (monomeric):Fc-KIH   (human) (rec.)
IL-2 (人) (单体):Fc-KIH (人) (重组)

HEK 293细胞

3 x 10 μg

10 μg

100 μg

AG-40B-0225

IL-2 (mouse) (monomeric):Fc-KIH   (human) (rec.)
IL-2 (小鼠) (单体):Fc-KIH (人) (重组)

HEK 293细胞

3 x 10 μg

10 μg

100 μg

TNF配体多聚体蛋白/MultimericLigands

内源性TNF超家族配体以膜的形式(如FasL、TRAIL、CD40L、OX40L)表现出活性,或通过与细胞(如APRIL)表面的蛋白聚糖结合来寡聚化分泌和激活。

MultimericLigands™由两个三聚体TNFSF配体组成,它们通过脂联素【ACRP30headless】的寡聚胶原结构域连接,模拟天然配体的自然膜辅助聚集。

产品速递

产品编号

产品名称

来源

规格

作用

AG-40B-0010

CD40L (human) (multimeric)   (rec.)
重组人CD40L(多聚体)

CHO 细胞

3 x 10 μg

有效的B细胞扩增工具

10 μg

AG-40B-0130

FasL (human) (multimeric)   (rec.)
重组人FasL(多聚体)

HEK 293细胞

3 x 10 μg

诱导人Jurkat T细胞的凋亡

10 μg

COMP-融合蛋白

COMP-融合蛋白基于软骨低聚基质蛋白(COMP)的五聚体化结构域(最小的盘绕结构域),通过一个特定的连接体与目标蛋白融合。AdipoGen Life Sciences利用这项技术生产出更具亲和力和生物活性的细胞因子。

产品速递

产品编号

产品名称

来源

规格

AG-40B-0147

COMP (rat):Angiopoietin-1   (human) (rec.)
重组型COMP (大鼠):血管生成素-1 (人)

CHO 细胞

5 x 10 µg

50 µg

10 μg

AG-40B-0181

VISTA (mouse):COMP (mouse)   (rec.) (His)
VISTA(小鼠):COMP(小鼠)(重组)(His)

HEK 293细胞

50 µg

Fc融合蛋白(野生型或非溶解性)

细胞因子序列与IgG(人或小鼠)Fc结构域的融合决定了其在体内持续循环的半衰期。Fc结构域独立折叠,可以提高伴侣分子在体外和体内的溶解度和稳定性。非溶解性Fc融合蛋白含有IgGs Fc片段的补体(C1q)和FcgR I结合位点的突变,这使得融合蛋白不会具有抗体靶向的细胞毒性(ADCC)和补体靶向的细胞毒性(CDC)。

 

产品速递

 

产品编号

产品名称

来源

规格

CHI-MF-120A4

CD152 [CTLA-4] (mouse):Fc   (mouse) (rec.) (non-lytic)
CD152 [CTLA-4] (小鼠):Fc (小鼠) (重组) (非溶解性)

NS1 细胞

100 μg

500 µg

CHI-MF-11135

IL-35 (mouse):Fc (human)   (rec.)
白介素35 (小鼠):Fc (人) (重组)

CHO细胞

5 μg

25 μg

AG-40B-0039

LAG-3 (mouse):Fc (mouse)   (rec.)
重组型LAG-3(小鼠):Fc(小鼠)

CHO细胞

50 μg

※以上产品仅供实验研究用

 

IL-6 ELISA试剂盒 IL-6 ELISA Kit

产品中心 > 生命科学 > 疾病研究 > 感染&自身免疫疾病

IL-6 ELISA试剂盒
IL-6 ELISA Kit

  • 产品特性
  • 相关资料
  • Q&A
  • 参考文献

高灵敏的IL-6定量(0.057 pg/mL)比色试剂盒IL-6 ELISA试剂盒                               IL-6 ELISA Kit



Enzo独特的IL-6(人),高灵敏度ELISA试剂盒(产品编号:ENZ-KIT178-0001)能够定量检测微量IL-6。 IL-6高灵敏度ELISA试剂盒可以在细胞培养上清液、血浆、血清和尿液中检测到低至0.057 pg/mL的IL-6。

白细胞介素-6(IL-6)是调节免疫系统和造血系统的重要细胞因子。人IL-6由T细胞、肥大细胞、单核细胞、巨噬细胞、成纤维细胞、内皮细胞、角质形成细胞及许多肿瘤细胞系表达。在急性期反应、对损伤和炎症的反应中起作用。 人IL-6刺激B细胞分化以产生抗体,促进激活T细胞的扩增,扩大造血细胞产物生成,并诱导急性期蛋白的表达。

IL-6(人)高灵敏度ELISA试剂盒是比色免疫测定试剂盒,3小时内得到结果。在450 nm读取吸光度。每96孔试剂盒可同时测量多达40个样品。



IL-6 ELISA试剂盒                               IL-6 ELISA Kit

IL-6高灵敏度ELISA试剂盒(ENZ-KIT178)标准曲线



IL-6 ELISA试剂盒                               IL-6 ELISA Kit



◆特点


● 高灵敏度的ELISA实现微量IL-6定量
● 操作方便的液体颜色编码试剂,减少失误
● 3小时内快速定量获得结果
● 高通量,每个试剂盒可处理多达40个样品,两次重复
● 即用型试剂和预包被板减少错误,节省时间



◆产品列表


产品编号

产品名称

包装

ENZ-KIT178-0001

IL-6 (human), high sensitivity ELISA kit
IL-6(人),高灵敏度ELISA试剂盒

96 wells



◆相关产品


产品编号

产品名称

包装

ENZ-KIT102-0001

CRP (human) ELISA kit
CRP (人) ELISA 试剂盒

96 wells


高灵敏ELISA试剂盒,灵敏度达8.876 ng/mL),用于定量CRP(炎症的早期生物标志物)。



产品编号

产品名称

包装

ENZ-KIT178-CTL

IL-6 High Sensitivity Controls
IL-6高灵敏度对照

1 Set


ENZ-KIT178-0001中的对照品。



免责声明

1. 本公司密切关注本网站发布的内容,但不保证发布内容的准确性、完整性、可靠性和最新性等。

2. 本公司不保证使用本网站期间不会出现故障或计算机病毒污染的风险。

3. 无论何种原因,使用本网站时给用户或第三方造成的任何不利或损害,本公司概不负责。此外,对于用户与其他用户或第三方之间因本网站发生的任何交易、通讯

3. 纠纷,本公司概不负责。

4. 本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗,仅可用于科研等非医疗目的。如任何用户将本网站提供的产品和服务用临床诊断或治

4. 疗,以及他特定的用途或行为,本公司概不保证其安全性和有效性,并且不负任何相关的法律责任。

LBIS Human IL-7 ELISA Kit 短时间/微量样品/高灵敏度检测人血清(血浆)中的IL-7

产品中心 > 生命科学 > 疾病研究 > 感染&自身免疫疾病

LBIS Human IL-7 ELISA Kit
短时间/微量样品/高灵敏度检测人血清(血浆)中的IL-7

  • 产品特性
  • 相关资料
  • Q&A
  • 参考文献

LBIS Human IL-7 ELISA KitLBIS Human IL-7 ELISA Kit                              短时间/微量样品/高灵敏度检测人血清(血浆)中的IL-7

短时间/微量样品/高灵敏度检测人血清(血浆)中的IL-7

FUJIFILM Wako Shibayagi Corporation的LBIS Cytokine ELISA Kit系列推出了新产品Human IL-7。对于现有产品因缺乏灵敏度而无法检测的正常样品和低浓度样品,新产品可以高灵敏度且重复性良好地进行检测。

IL-7主要由骨髓、胸腺、淋巴器官或组织的基质细胞等非造血细胞产生,是诱导干细胞分化为免疫细胞的细胞因子。成熟体由152个氨基酸组成。CD4+、CD8+两种细胞的增殖和发生、促进抗病毒活性,还与类风湿关节炎、慢性结肠炎的产生以及与嗜酸性粒细胞活性引起的哮喘有关。另外,作为抗癌药和免疫检查点相关药物联合治疗中的助推因子,高灵敏度IL-7的检测,在NK细胞、B细胞和T细胞的增强作用物质的探索和研究中也备受期待。

特点


● 不适用于卡塔赫纳生物安全议定书(不含杆状病毒)

● 微量样品的检测

● 可短时间检测(总反应时间:2 h 50 min)

● 使用环保防腐剂

● 准确性和重复性高



◆性能

 样品

 人血清/血浆(肝素/EDTA)

 校准曲线范围

 1.50~236 pg/mL

 Assay内差异(5次检测,2个样品)

 平均C.V.   值:不足15%

 Assay间差异(3次检测,3个样品,4天)

 平均C.V.   值:不足15%

◆数据


■ 人样品检测(例)

Sample No.

检测值

Sample No.

检测值

1

3.9

7

3.78

2

2.44

8

11

3

7.59

9

40

4

6.21

10

10

5

9.36

11

3.5

6

5.35

人正常血清,2重检测,单位:pg/mL

试剂盒组成


● 抗体固定96孔板···········································96 wells(8×12)×1张

● 人IL-7标准品······················································································1瓶

● 缓冲液···················································································60 mL×1瓶

● 生物素结合抗IL-7抗体······································································1瓶

● 过氧化物酶·亲和素结合物···············································150 μL×1瓶

● 显色液(TMB)··································································12 mL×1瓶

● 反应终止液(1 mol/L H2SO4)·····································12 mL×1瓶

● 浓缩清洗液(10×)···························································100 mL×1瓶

◆产品列表

产品编号

厂家编号

产品名称

包装

637-50441

AKH-IL7

LBIS Human IL-7 ELISA Kit
人IL-7 ELISA试剂盒

96 tests

相关产品

产品编号

厂家编号

产品名称

标准曲线范围(pg/mL)

包装

635-42311

AKH-IL6

LBIS Human IL-6 ELISA Kit
人IL-6 ELISA试剂盒

1.16~500

96 tests

632-42321

AKH-IL8

LBIS Human IL-8 (CXCL8)ELISA Kit
人IL-8(CXCL8)ELISA试剂盒

0.686~500

96 tests

639-42331

AKHTNFA

LBIS Human TNF-α ELISA Kit
人 TNF-α ELISA试剂盒

2.05~500

96 tests

631-40831

AKHVEGF

LBIS Human VEGF ELISA Kit
人VEGF ELISA试剂盒

1.10~800

96 tests

631-47891

AKHIFNG

LBIS Human IFN-γ ELISA Kit
人IFN-γELISA试剂盒

0.768~75.0

96 tests


 


免责声明

1. 本公司密切关注本网站发布的内容,但不保证发布内容的准确性、完整性、可靠性和最新性等。

2. 本公司不保证使用本网站期间不会出现故障或计算机病毒污染的风险。

3. 无论何种原因,使用本网站时给用户或第三方造成的任何不利或损害,本公司概不负责。此外,对于用户与其他用户或第三方之间因本网站发生的任何交易、通讯

3. 纠纷,本公司概不负责。

4. 本网站可提供的所有产品和服务均不得用于人体或动物的临床诊断或治疗,仅可用于科研等非医疗目的。如任何用户将本网站提供的产品和服务用临床诊断或治

4. 疗,以及他特定的用途或行为,本公司概不保证其安全性和有效性,并且不负任何相关的法律责任。