抗体/试剂/诊断抗体原料,Recombinant human IL-15 protein (Active, HEK293)

发表于2024年3月21日由上海金畔生物科技有限公司

品牌：Bioss/博奥森 | 货号：JP-013

Recombinant human IL-15 protein (Active, HEK293)

产品编号

JP-013

产品分类

重组蛋白

英文名称

Recombinant human IL-15 protein (Active, HEK293)

中文名称

重组人白介素15 (活性的, Tag free)

英文别名

rhIL-15; Interleukin-15; IL 15; Interleukin 15; Interleukin15; MGC9721; IL15; IL15_HUMAN. ;Recombinant human IL-15 protein (Active, HEK293)

中文别名

人白介素15重组蛋白; 重组人白介素15; 人重组白介素15;

纯化方法

检测分子量

14-15 kDa

GeneID

3600

Swiss

P40933

浓度

＞0.5 mg/ml

储存液

Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization.

保存条件

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution.

Subunit

Subcellular Location

Isoform IL15-S48AA: Secreted. Isoform IL15-S21AA: Cytoplasm. Nucleus. Note=IL15-S21AA is not secreted, but rather is stored intracellularly, appearing in the nucleus and cytoplasmic components.

Tissue Specificity

Most abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15-S21AA is preferentially expressed in tissues such as testis and thymus.

Similarity

Belongs to the IL-15/IL-21 family.

Database links

Entrez Gene: 3600 Human

Omim: 600554 Human

SwissProt: P40933 Human

Unigene: 654378 Human

多肽活性

Yes

蛋白质与多肽-多肽序列

49-162/162

小分子偶联蛋白-蛋白载体

标签

Tag free

纯度

>95% as determined by SDS-PAGE

内毒素

<0.5 EU/μg as determined by LAL.

重组蛋白-表达系统

HEK293 cell

复溶

Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.

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抗体/试剂/诊断抗体原料,Recombinant human IL-2 protein (Active, HEK293)

发表于2024年3月21日由上海金畔生物科技有限公司

品牌：Bioss/博奥森 | 货号：JP-017-10ug

产品编号

JP-017

产品分类

重组蛋白

英文名称

Recombinant human IL-2 protein (Active, HEK293)

中文名称

重组人白介素2 (活性的, Tag free)

英文别名

Interleukin-2; Interleukin 2; Interleukin2; rhIL-2; T-cell growth factor; T Cell Growth Factor; Aldesleukin; IL 2; IL2; Lymphokine; POIL2; T Cell Growth Factor; TCGF; Involved in regulation of T cell clonal expansion; IL2_HUMAN. ;Recombinant human IL-2 protein (Active, HEK293)

中文别名

人白介素2重组蛋白; 重组人白介素2; 人重组白介素2; 重组人白介素2（IL-2）;

蛋白细胞定位

分泌型蛋白

纯化方法

理论分子量

15kDa

检测分子量

17 kDa

GeneID

3558

Swiss

P60568

浓度

＞0.5 mg/ml

储存液

Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization.

保存条件

Subunit

Subcellular Location

Secreted.

DISEASE

Note=A chromosomal aberration involving IL2 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with involves TNFRSF17.

Similarity

Belongs to the IL-2 family.

Database links

Entrez Gene: 3558 Human

Entrez Gene: 16183 Mouse

Entrez Gene: 116562 Rat

Omim: 147680 Human

SwissProt: P60568 Human

SwissProt: P04351 Mouse

SwissProt: P17108 Rat

Unigene: 89679 Human

Unigene: 14190 Mouse

Unigene: 9871 Rat

背景资料

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]