前列腺素 E2 酶联免疫试剂盒
PGE2 ELISA kit
- 产品特性
- 相关资料
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前列腺素 E2 酶联免疫试剂盒
PGE2 ELISA kit
用于炎症和类花生酸研究的高灵敏度前列腺素E2酶联免疫试剂盒。
研究背景:前列腺素 E2(PGE2)由于其在炎症、癌症、动脉粥样硬化、自身免疫性疾病和脓毒症中具有重要地位而被广泛研究。氧化的花生四烯酸通过前列腺素合成酶(COX-1和COX-2)生成前列腺素 H2(PGH2),被前列腺素合成酶进一步代谢成主要产物前列腺素 E2(PGE2)。前列腺素 E2(PGE2)通过与细胞表面的 G-蛋白偶联受体(EP1、EP2、EP3 和 EP4)的结合来介导自分泌和旁分泌的信号传导,从而调节磷脂酶C和腺苷酸环化酶活性。PGE2 作为一种治疗靶点,无论是通过 COX 抑制剂(NSAIDS)调节其合成,还是通过下调其与受体结合或结合拮抗剂,都引起了人们极大的兴趣。在各种组织中产生的前列腺素 E2(PGE2)已在多种生理过程中表现出了调节作用,包括在肾脏中尿钠排泄,血管中平滑肌的弹性,以及单核细胞和巨噬细胞对损伤组织的炎症作用。
◆产品特点
● 高灵敏度测定,可检测最少 13.4 pg/mL 的前列腺素 E2
● 3小时内即可获得多达37个样本重复检测的高通量格式的结果
● 广泛引用于同行评审文献中
● 准备使用的液体颜色编码试剂以便减少错误发生
● 每次使用和不同批次产品获得良好重复性的结果
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[1] |
Colon cancer-derived myofibroblasts increase endothelial cell migration by glucocorticoid-sensitive secretion of a pro-migratory factor: Z. Drebert, et al.; Vascul. Pharmacol. 89, 19 (2017), Application(s): Determine the concentrations of prostanoids in conditioned medium from myofibroblasts and HUVECs, and in HUVEC lysates, Abstract; |
[2] |
Expression of toll-like receptor-1 by bradykinin in human gingival fibroblasts: J.A. Arreguin-Cano T; Int. J. Clin. Exp. Pathol. 10, 1283 (2017), Application(s): Measurement of PGE2 in supernatant., Full Text |
[3] |
Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome: H.C. Clark, et al.; Stem Cell Res. Ther. 8, 69 (2017), Application(s): Measurement of PGE2 in supernatant of human and feline cells., Abstract; Full Text |
[4] |
Novel augmentation by bufalin of protein kinase C-induced cyclooxygenase-2 and IL-8 production in human breast cancer cells: H.T. Chen, et al.; Innate Immun. 23, 54 (2017), Abstract; Full Text |
[5] |
Prostaglandin E2 stimulates the expression of cumulus expansion-related genes in pigs: the role of protein kinase B: M. Blaha, et al.; Prostaglandins Other Lipid Mediat. 130, 38 (2017), Application(s): ELISA using pig samples, Abstract; |
[6] |
A positive feedback loop between progesterone and microsomal prostaglandin E synthase-1-mediated PGE2 promotes production of both in mouse granulosa cells: K. Tamura, et al.; Prostaglandins Other Lipid Mediat. 123, 56 (2016), Application(s): Measurement of PGE2 in the culture media, Abstract; |
[7] |
Anti-inflammatory effects of 6′-O-acetyl mangiferin from Iris rossii Baker via NF-κb signal blocking in lipopolysaccharide-stimulated RAW 264.7 cells: J.H. Jang, et al.; Chem. Biol. Interact. 2797, 30303 (2016), Application(s): Determination of PGE2 production, Abstract; |
[8] |
Dimethyl fumarate activates the prostaglandin EP2 receptor and stimulates cAMP signaling in human peripheral blood mononuclear cells: S.E. Fiedler, et al.; Biochem. Biophys. Res. Commun. 475, 19 (2016), Application(s): Supernatant PGE2 was measured, Abstract; |
[9] |
Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia: Y.S. Chiou, et al.; Free. Radic. Biol. Med. 94, 1 (2016), Application(s): Measurement of prostaglandin E2 (PGE2) level in culture medium, Abstract; |
[10] |
Effects of Almond- and Olive Oil-Based Docosahexaenoic- and Vitamin E-Enriched Beverage Dietary Supplementation on Inflammation Associated to Exercise and Age: X. Capo, et al.; Nutrients 8, 619 (2016), Application(s): Cytokine, Eicosanoids and Adhesion Molecules Determination, plasma, Abstract; Full Text |
[11] |
Enhanced anti-inflammatory activity of brown seaweed Laminaria japonica by fermentation using Bacillus subtilis: H.T.V. Lin, et al.; Process Biochem. (2016), Application(s): Measurement of prostaglandin E2 (PAGE2), cell supernatant, |
[12] |
Grid-like surface structures in thermoplastic polyurethane induce anti-inflammatory and anti-fibrotic processes in bone marrow-derived mesenchymal stem cells: Y. Roger, et al.; Colloids Surf. B Biointerfaces 148, 104 (2016), Application(s): ELISA using human bone marrow-derived mesenchymal stem cell supernatant, Abstract; |
[13] |
Implantation and pregnancy outcome of Sprague-Dawley rats fed with low and high salt diet: G.O. Oludare, et al.; Middle East Fertil. Soc. J. (2016), Application(s): Measured rat serum PGE2 levels, |
[14] |
In vitro bioactive properties of phlorotannins recovered from hydrothermal treatment of Sargassum muticum: M.P. Casas, et al.; Sep. Purif. Technol. 167, 117 (2016), Application(s): Determination of the amount of PGE2 in thawed plasma supernatants, |
[15] |
Isolation and Identification of a Flavone Apigenin from Marine Red Alga Acanthophora spicifera with Antinociceptive and Anti-Inflammatory Activities: G.A. El Shoubaky, et al.; J. Exp. Neurosci. 10, 21 (2016), Application(s): TNF-α measured in mouse blood samples, Abstract; Full Text |
[16] |
Local intra-uterine Ang-(1-7) infusion attenuates PGE2 and 6-keto PGF1α in decidualized uterus of pseudopregnant rats: K.B. Brosnihan, et al.; Reprod. Biol. Endocrinol. 14, 68 (2016), Application(s): Assaying tissue extracts, Abstract; Full Text |
[17] |
MRI-Based Assessment of Intralesional Delivery of Bone Marrow-Derived Mesenchymal Stem Cells in a Model of Equine Tendonitis: A. Scharf, et al.; Stem Cells Int. 2016, 1 (2016), Application(s): Assessing the ability of MSCs to modulate the inflammatory response, Abstract; Full Text |
[18] |
Resokaempferol-mediated anti-inflammatory effects on activated macrophages via the inhibition of JAK2/STAT3, NF-κB and JNK/p38 MAPK signaling pathways: Q. Yu, et al.; Int. Immunopharmacol. 38, 104 (2016), Application(s): PGE2 was measured in mouse supernatant, Abstract; |
[19] |
The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation: X. Wang, et al.; PLoS One 12, e1005803 (2016), Application(s): PGE2 measurement in cell lysates, Abstract; Full Text |
[20] |
Antagonizing Effects of Aspartic Acid against Ultraviolet A-Induced Downregulation of the Stemness of Human Adipose Tissue-Derived Mesenchymal Stem Cells: K. Jung, et al.; PLoS One 10, e0124417 (2015), Application(s): ELISA using human culture supernatant , Abstract; Full Text |
[21] |
Anti-inflammatory effect of desoxo-narchinol-A isolated from Nardostachys jatamansi against lipopolysaccharide: J.Y. Shin, et al.; Int. Immunopharmacol. 29, 730 (2015), Application(s): PGE2 level was measured by ELISA in mice, Abstract; |
[22] |
Effectiveness of the combinational treatment of Laminaria japonica and Cistanche tubulosa extracts in hair growth: K. Shin, et al.; Lab. Anim. Res. 31, 24 (2015), Application(s): ELISA using mouse exudate, Abstract; Full Text |
[23] |
Insight into the molecular mechanism of an herbal injection by integrating network pharmacology and in vitro: Y.M. Ma, et al.; J. Ethnopharmacol. 173, 91 (2015), Application(s): ELISA using mouse RAW264.7 cells , Abstract; |
[24] |
Lipin-1 contributes to modified low-density lipoprotein-elicited macrophage pro-inflammatory responses: A.R. Navratil, et al. ; Atherosclerosis 242, 424 (2015), Application(s): ELISA using mouse cell culture supernatant, Abstract; |
[25] |
Molecular characterization and knock-down of salmon louse (Lepeophtheirus salmonis) prostaglandin E synthase: C. Eichner, et al.; Exp. Parasitol. 159, 79 (2015), Application(s): ELISA Kit measuring PGE2 levels in salmon lice, Abstract; |
[26] |
Prostaglandin E2 Production and T Cell Function in Mouse Adenovirus Type 1 Infection following Allogeneic Bone Marrow Transplantation: M.K. McCarthy, et al.; PLoS One 10, e0139235 (2015), Application(s): PGE2 concentration in bronchoalveolar lavage fluid , Abstract; Full Text |
[27] |
Role of gastric acid inhibition, prostaglandins and endogenous-free thiol groups on the gastroprotective effect of a proteolytic fraction from Vasconcellea cundinamarcensis latex: A. Silva, et al.; J. Pharm. Pharmacol. 67, 133 (2015), Application(s): EIA using rat tissue samples, Abstract; Full Text |
[28] |
Supplement of 5-hydroxytryptophan before induction suppresses inflammation and collagen-induced arthritis: T.H. Yang, et al. ; Arthritis. Res. Ther. 17, 364 (2015), Application(s): Measurement of PGE2 in mice serum samples, Abstract; Full Text |
[29] |
The cancer pain related factors affected by celecoxib together with cetuximab in head and neck squamous cell carcinoma: Y. Yang, et al.; Biomed. Pharmacother. 70, 181 (2015), Application(s): ELISA using human culture medium, Abstract; |
[30] |
The Receptor CMRF35-Like Molecule-1 (CLM-1) Enhances the Production of LPS-Induced Pro-Inflammatory Mediators during Microglial Activation: A. Ejarque-Ortiz, et al.; PLoS One 10, e0123928 (2015), Application(s): ELISA using mouse microglial supernatant, Abstract; Full Text |
[31] |
Inhibition of COX-2 and PGE2 in LPS-stimulated RAW264.7 cells by lonimacranthoide VI, a chlorogenic acid ester saponin: F. Guan, et al.; Biomed. Rep. 2, 760 (2014), Application(s): Assay of LPS-stimulated RAW264.7 macrophages, Abstract; Full Text |
[32] |
Possible roles of COX-1 in learning and memory impairment induced by traumatic brain injury in mice: J. Shang, et al.; Braz. J. Med. Biol. Res. 47, 1050 (2014), Application(s): Analysis of PGE2 levels in mouse hippocampus tissue, Abstract; Full Text |
[33] |
Prostaglandin E2 promotes features of replicative senescence in chronically activated human CD8+ T cells: J.P. Chou, et al.; PLoS One 9, e99432 (2014), Application(s): EIA using cell culture supernatants, Abstract; Full Text |
[34] |
Anti-inflammatory, antioxidative and matrix metalloproteinase inhibitory properties of 20(R)-ginsenoside Rh2 in cultured macrophages and keratinocytes: W.Y. Choi, et al.; J. Pharm. Pharmacol. 65, 310 (2013), Application(s): EIA using culture supernatants, Abstract; |
[35] |
Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity: T. Li, et al.; Med. Oncol. 30, 663 (2013), Application(s): EIA using culture supernatants, Abstract; |
[36] |
Melanoma-educated CD14+ cells acquire a myeloid-derived suppressor cell phenotype through COX-2-dependent mechanisms: Y. Mao, et al.; Cancer Res. 73, 3877 (2013), Application(s): EIA using culture supernatants, Abstract; |
[37] |
Microenvironment generated during EGFR targeted killing of pancreatic tumor cells by ATC inhibits myeloid-derived suppressor cells through COX2 and PGE2 dependent pathway: A. Thakur, et al.; J. Transl. Med. 11, 35 (2013), Application(s): EIA using culture supernatants from 3D co-cultures, Abstract; Full Text |
[38] |
Prostaglandin E2 alteration in contraceptive consumers: as a risk factor for inflammatory diseases: M.S. Pour, et al.; Arch. Gynecol. Obstet. 287, 1031 (2013), Application(s): EIA using human serum, Abstract; |
[39] |
Transmigration of Neural Stem Cells across the Blood Brain Barrier Induced by Glioma Cells: M. Díaz-Coránguez, et al.; PLoS One 8, e60655 (2013), Application(s): Quantification was done in 4 day CM derived from rat astrocytes and glioma C6 cells using ELISA, Abstract; Full Text |
[40] |
XH-14, a novel danshen methoxybenzo[b]furan derivative, exhibits anti-inflammatory properties in lipopolysaccharide-treated RAW 264.7 cells: G.M. Park, et al.; J. Inflamm. 10, 1 (2013), Application(s): EIA using culture supernatants, Abstract; Full Text |
[41] |
Acacetin protects dopaminergic cells against 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine-induced neuroinflammation in vitro and in vivo: H.G. Kim, et al.; Biol. Pharm. Bull. 35, 1287 (2012), Application(s): EIA using culture supernatants, Abstract; Full Text |
[42] |
Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO: T. Li, et al.; Cancer Lett. 318, 154 (2012), Application(s): EIA using culture supernatants, Abstract; |
[43] |
Lycorine inhibits lipopolysaccharide-induced iNOS and COX-2 up-regulation in RAW264.7 cells through suppressing P38 and STATs activation and increases the survival rate of mice after LPS challenge: J. Kang, et al.; Int. Immunopharmacol. 12, 249 (2012), Application(s): EIA using culture supernatants, Abstract; |
[44] |
Matrix metalloproteinase-19 is a key regulator of lung fibrosis in mice and humans: G. Yu, et al.; Am. J. Respir. Crit. Care Med. 186, 752 (2012), Application(s): PGE2 from mice BAL was measured, Abstract; |
[45] |
Delta6-desaturase (FADS2) deficiency unveils the role of omega3- and omega6-polyunsaturated fatty acids: W. Stoffel, et al.; EMBO J. 27, 2281 (2008), Application(s): EIA using tissue, Abstract; |
[46] |
Anti-inflammatory effects of isoflavone powder produced from soybean cake: T.H. Kao, et al.; J. Agric. Food Chem. 55, 11068 (2007), Application(s): EIA using peritoneal exudate fluid and peritoneal exudate cell supernatant, Abstract; |
[47] |
Celecoxib inhibits Cdx2 expression and prevents gastric cancer in Helicobacter pylori-infected Mongolian gerbils: S. Futagami, et al.; Digestion 74, 187 (2006), Abstract; |
[48] |
Spinal inflammatory hyperalgesia is mediated by prostaglandin E receptors of the EP2 subtype: H. Reinold, et al.; J. Clin. Invest. 115, 673 (2005), Application(s): PGE2 from the thoracolumbar segment of the spinal cord was measured, mice, Abstract; Full Text |
[49] |
Effect of a selective cyclooxygenase-2 inhibitor, nimesulide, on the growth of lung tumors and their expression of cyclooxygenase-2 and peroxisome proliferator- activated receptor-gamma: M.S. Shaik, et al.; Clin. Cancer Res. 10, 1521 (2004), Application(s): EIA using mouse tissue, Abstract; |
[50] |
Nonopioid actions of intrathecal dynorphin evoke spinal excitatory amino acid and prostaglandin E2 release mediated by cyclooxygenase-1 and -2: L. Koetzner, et al.; J. Neurosci. 24, 1451 (2004), Application(s): EIA using dialysate, Abstract; |
[51] |
Differential expression of platelet-activating factor acetylhydrolase in macrophages and monocyte-derived dendritic cells: S. Al-Darmaki, et al.; J. Immunol. 170, 167 (2003), Application(s): EIA using human culture supernatants, Abstract; |
[52] |
Inhibition of cyclooxygenase-2 by rofecoxib attenuates the growth and metastatic potential of colorectal carcinoma in mice: M. Yao, et al.; Cancer Res. 63, 586 (2003), Application(s): Concentration of PGE2 in splenic tumor cystosolic fractions were determined using mouse tissue, Abstract; |
[53] |
Microsomal prostaglandin E synthase-1 is a major terminal synthase that is selectively up-regulated during cyclooxygenase-2-dependent prostaglandin E2 production in the rat adjuvant-induced arthritis model: D. Claveau, et al.; J. Immunol. 170, 4738 (2003), Application(s): PGE2 production was determined by enzyme immunoassay analysis using rat tissue, Abstract; Full Text |
[54] |
Increased levels of the pro-inflammatory prostaglandin PGE2 in CSF from ALS patients: G. Almer, et al.; Neurology 58, 1277 (2002), Application(s): EIA using cerebral spinal fluid, Abstract; |
[55] |
The effects of periodontal therapy on intracrevicular prostaglandin E2 concentrations and clinical parameters in pregnancy: F. Yalcin, et al.; J. Periodontol. 73, 173 (2002), Application(s): EIA using gingival crevicular fluid, Abstract; |
[56] |
Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells: M. Akhtar, et al.; Cancer Res. 61, 2399 (2001), Application(s): EIA using cell culture supernatant, Abstract; Full Text |
[57] |
Inflammatory agonists induce cyclooxygenase type 2 expression by human neutrophils: C.G. Maloney, et al.; J. Immunol. 160, 1402 (1998), Application(s): EIA using human cell culture supernatant, Abstract; |
[58] |
Selective cyclooxygenase-2 inhibition by nimesulide in man: L. Cullen, et al.; J. Pharmacol. Exp. Ther. 287, 578 (1998), Application(s): EIA using plasma, Abstract; |
产品编号 | 产品名称 | 产品规格 | 产品等级 | 备注 |
ADI-900-001 | PGE2 ELISA kit 前列腺素E2酶联免疫试剂盒 |
96 wells | – | – |
ADI-901-001 | PGE2 ELISA kit 前列腺素E2酶联免疫吸附试剂盒 |
5×96 wells | – | – |
ENZ-KIT179-0200 | PLAQPRO™ Lp-PLA2 Assay PLAQPRO™ Lp-PLA2 化验 |
200 tests | – | – |
ADI-930-001 | PGE2 high sensitivity ELISA kit PGE2高灵敏度酶联免疫试剂盒 |
96 wells | – | – |
ADI-931-001 | PGE2 high sensitivity ELISA kit 前列腺素E2 高灵敏度 ELISA kit |
5×96 wells | – | – |
ADI-900-068 | LTB4 ELISA kit 白三烯B4 酶联免疫试剂盒 |
96 wells | – | – |
ADI-901-068 | LTB4 ELISA kit 白三烯B4 酶联免疫试剂盒 |
5×96 wells | – | – |
ADI-900-092 | 11-dehydro-TXB2 ELISA kit 11-脱氢-血栓烷素B2 ELISA试剂盒 |
96 wells | – | – |
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