有轻微特殊气味。微有吸湿性。遇热易熔化。溶于水和乙醇

聚乙二醇（PEG）是一种亲水性的聚合物。它可以通过环氧乙烷的阴离子开环聚合而被轻易的合成为不同的分子量和并带有各种端基。当交联成网络时，PEG可具有高的含水量，形成“水凝胶”。水凝胶的形成可通过电离辐射交联PEG或通过PEG大分子单体与反应性链端的共价交联而引发。PEG引其不会触发免疫反应而成为一种适合于生物学应用的材料。

通常用于修饰治疗蛋白和多肽，以增加其溶解性和降低其毒性。

更环保地选择性氟化乙醯胺的氟化溶剂

Polyethylene glycol (PEG) is a hydrophilic polymer. It can be easily synthesized by the anionic ring opening polymerization of ethylene oxide, into a range molecular weights and variety of end groups. When crosslinked into networks PEG can have high water content, forming “hydrogels”. Hydrogel formation can be initiated by either crosslinking PEG by ionizing radiation or by covalent crosslinking of PEG macromers with reactive chain ends. PEG is a suitable material for biological applications because it does not trigger an immune response.