Products > 96 Well Crystallization Plates > Swissci > LCP Lipidic Cubic Phase Screening
LCP Lipidic Cubic Phase Screening
Applications
- Lipidic cubic phase crystallization
Features
- UVP cover film (UV compatible)
- No cross contamination
- Membrane protein crystallization
- 6 mm diameter drop well area
- 0.1 mm (100 μm) deep drop well when LCP plate is sealed
- Maximum drop volume is 1.6 microliters per well
应用
脂质立方相结晶
UVP覆盖膜(UV兼容)
无交叉污染
膜蛋白结晶
6 mm 直径滴孔区
当 LCP 板被密封时,0.1 毫米(100 微米)深的水滴井
最大滴体积为每孔 1.6 微升
Description
The Lipidic Cubic Phase Crystallization (LCP) plate facilitates the automation and increased throughput of LCP crystallization set-ups. This novel system enables LCP screening to be performed accurately and with ease – using manual – or automated systems to complete the delivery of the solutions.
Working with innovative scientists Professor Gebhard Schertler and Pat Edwards from the MRC laboratory in Cambridge, Swissci AG developed a new system for setting up LCP screens.
The Swissci LCP plate ensures crystallography set-up is fast, cost effective and robotically adaptable. In addition Ultra Violet light can be used with the glass / UVP polymers to visualize proteins without the light scattering associated with traditional polymeric solutions.
The LCP technique for crystallizing membrane proteins can be difficult and time-consuming to set up as it utilizes highly viscous lipid mesophases to reconstitute proteins. Swissci AG and MRC overcame these problems with the LCP plate. This product combines an easy to use sandwich system with dedicated coupling tapes and thin film UVP cover plates. It conforms to SBS standards and thus is perfect for modern automation applications where high throughput is required.
The Advantages of the LCP plate
• Ready to use the plate fits laboratory robotics and uses a Swissci unique polymer to ensure UV visualization is not compromised by polarization.
• Easy sealing with dry tabbed adhesive tape exposure and thin UVP cover film. Included in the kit is a plate leveling device to ensure the cover is perfectly adhered to the bottom LCP plate.
• No cross contamination and SBS standard.
• Unique low tack plate security allows for the sandwich plate to be removed from the base plate when required – in-situ x-ray data collection and structure determination is then enabled.
Here’s a description of the LCP plate from bottom to top. a) An SBS standard base plate frame support. b) 0.7 mm thick UVP plastic slide drop support containing all 96 drop wells with 0.1 mm thick layer of low tack sealant (no sealant in drop area). Flat, circular, 6 mm diameter drop wells to contain the LCP, sample and reagent. c) Removable brown/tan paper protects sealant until plate is ready to use. d) 0.1 mm thick UVP sealing film. e) Removable protective dust cover. The kit is completed with a Swissci plate leveling device.
To use the LCP plate, pipette LCP, sample and reagent into the 96 drop wells. Peel back and remove the brown/tan paper to expose the adhesive. Place the sealing film onto the LCP plate. Remove the protective film for viewing.
Maximum drop volume is 1.6 microliters per well.
脂质立方相结晶 (LCP) 板有助于实现 LCP 结晶设置的自动化并提高产量。这种新颖的系统使 LCP 筛选能够准确、轻松地进行 – 使用手动或自动系统来完成解决方案的交付。
Swissci AG 与剑桥 MRC 实验室的创新科学家 Gebhard Schertler 教授和 Pat Edwards 教授合作,开发了一种用于设置 LCP 屏幕的新系统。
Swissci LCP 板确保晶体学设置快速、经济高效且机器人适应性强。此外,紫外光可与玻璃/UVP 聚合物一起使用,以显示蛋白质,而不会产生与传统聚合物溶液相关的光散射。
用于结晶膜蛋白的 LCP 技术可能既困难又耗时,因为它利用高粘性脂质中间相来重建蛋白质。 Swissci AG 和 MRC 用 LCP 印版克服了这些问题。该产品将易于使用的夹层系统与专用耦合带和薄膜 UVP 盖板相结合。它符合 SBS 标准,因此非常适合需要高吞吐量的现代自动化应用。
LCP板的优点
• 即用型板适合实验室机器人并使用 Swissci 独特的聚合物来确保紫外线可视化不会因偏振而受到影响。
• 使用干燥的标签胶带暴露和薄的 UVP 覆盖膜轻松密封。套件中包含一个平板校平装置,以确保盖子完美地粘附在底部 LCP 平板上。
• 无交叉污染和SBS 标准。
• 独特的低粘性板安全性允许在需要时将夹层板从基板上移除——然后启用原位 X 射线数据收集和结构确定。
这是 LCP 板从下到上的描述。 a) SBS 标准底板框架支撑。 b) 0.7 毫米厚的 UVP 塑料载玻片液滴支架,包含所有 96 个液滴孔和 0.1 毫米厚的低粘性密封剂层(液滴区域没有密封剂)。扁平、圆形、直径为 6 毫米的滴孔,用于容纳 LCP、样品和试剂。 c) 可移除的棕色/棕褐色纸可保护密封胶,直到印版准备好使用。 d) 0.1 毫米厚的 UVP 密封膜。 e) 可拆卸的防尘罩。该套件配有 Swissci 板调平装置。
要使用 LCP 板,请将 LCP、样品和试剂移入 96 个滴孔中。剥开并去除棕色/棕褐色纸以露出粘合剂。将密封膜放在 LCP 板上。取下保护膜进行查看。
最大滴体积为每孔 1.6 微升。
HR3-186 Swissci Lipidic Cubic Phase Screening Kit
CAT NO
HR3-186
NAME
DESCRIPTION
20 plate case
PRICE
$422.00
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