TDB–Polysucrose 聚蔗糖

Dextran, epichlorohydrin cross-linked polymer

葡聚糖、表氯醇交联聚合物

CAS number: 26873-85-8

Polysucrose is supplied as a white powder which is freely soluble in water and electrolyte solutions. Many investigators have considered polysucrose to be a suitable molecule for studying glomerular physiology since it is biocompatible and not readily degraded in the blood stream. Further it has conformational properties more like proteins. Polysucrose (and particularly FITC-and TRITC-labelled polysucrose) have been used extensively in studies of vascular permeability, in particular glomerular permselectivity and has been reviewed. Polysucroses have been used for many decades for such purposes as gradient centrifugation of cells and organelles, nucleic acid hybridization, as a hapten carrier, concentration dialysis, to support growth of cell lines and phase partitioning.

聚蔗糖以白色粉末形式提供，可自由溶于水和电解质溶液。 许多研究人员认为聚蔗糖是研究肾小球生理学的合适分子，因为它具有生物相容性并且不容易在血流中降解。 此外，它具有更像蛋白质的构象特性。 聚蔗糖（尤其是 FITC 和 TRITC 标记的聚蔗糖）已广泛用于血管通透性研究，特别是肾小球渗透选择性研究，并已进行了审查。 几十年来，聚蔗糖已被用于细胞和细胞器的梯度离心、核酸杂交、作为半抗原载体、浓缩透析等目的，以支持细胞系的生长和相分配。