Q-dextran is a polycationic derivative of dextran. These derivatives are distinct from DEAE-dextrans in that they only contain quaternary amine groups. Unlike DEAE-dextrans, Q-dextrans will be charged over a wide range of pH (pH 4-10). Q-dextrans will also have a much stronger net charge than corresponding DEAE-dextrans. All batches are checked for molecular weight, degree of substitution and loss on drying. TdB Labs produce Q-dextran from 4 kDa to 150 kDa. Q-dextrans are supplied as a white powder.

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CAS号：不可用

Q-葡聚糖以粗白色粉末形式提供，易溶于水。氮含量约为。

2%（通过元素分析），相当于每四个季铵基团大约一个

葡萄糖单位。氮含量为 1.5 – 2.5%。与 DEAE-dextrans 不同，Q-dextrans 将被收取广泛的费用

pH 范围（pH 4-10）。它们还具有更强的净电荷，从而在系统中提供增强的响应

这种效果很重要。波利卡蒂

Q-葡聚糖是葡聚糖的聚阳离子衍生物。这些衍生物与 DEAE-葡聚糖的不同之处在于它们仅包含季胺基团。与 DEAE-葡聚糖不同，Q-葡聚糖将在很宽的 pH 值范围内（pH 4-10）带电。 Q-dextrans 的净电荷也比相应的 DEAE-dextrans 强得多。检查所有批次的分子量、取代度和干燥损失。 TdB Labs 可生产 4 kDa 至 150 kDa 的 Q-葡聚糖。 Q-葡聚糖以白色粉末形式提供。

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Structure
Q-dextrans are synthesised by reacting dextran fractions with 2,3-epoxypropyltrimethylammonium chloride. The nitrogen content is approximately 2% which corresponds to one quaternary ammonium group for every four glucose units.

Storage and stability
Q-dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.

Solubility
Q-dextran dissolves readily in water.

Application
Polycationic products exhibit a wide variety of effects in cellular systems and are of interest as adjuvants in vaccines. Q-dextran has a much stronger net charge than corresponding DEAE-dextrans and will thus give enhanced responses in systems where this effect is important. Read more about application here.

结构
Q-葡聚糖是通过葡聚糖组分与 2,3-环氧丙基三甲基氯化铵反应合成的。 氮含量约为 2%，对应于每四个葡萄糖单位一个季铵基团。

储存和稳定性
Q-葡聚糖在环境温度下在密封良好的容器中干燥储存时可稳定保存 6 年以上。

溶解度
Q-葡聚糖易溶于水。

应用
聚阳离子产品在细胞系统中表现出多种作用，并且在疫苗中作为佐剂受到关注。 Q-葡聚糖的净电荷比相应的 DEAE-葡聚糖强得多，因此在这种效应很重要的系统中会增强响应。 在此处阅读有关应用程序的更多信息。

References