TDB–CM-dextran
CAS Number: 39422-83-8
CM-dextran consists of a dextran backbone substituted with carboxymethyl substituents imparting a polyanionic character to the product. All batches are checked for molecular weight, degree of substitution and loss on drying. TdB Labs produce CM-dextrans from 4 kDa to 150 kDa. CM-dextran is supplied as a white powder.
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Structure
CM-dextrans are manufactured by reacting selected dextran fractions with an activated carboxymethyl derivative in alkali. This leads to the introduction of O-carboxymethyl groups along the dextran chain. The carboxyl content is approximately 5% which is equivalent to about one CM group for every 5 five glucose units. Higher degrees of substitution may be achieved if required.
Storage and stability
CM-dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature.
Solubility
CM-dextran dissolves readily in water.
Application
CM-dextran can be used as stabilisers for sensitive biopolymers, as non-toxic ingredients in formulations, as reagents for binding cations (inorganic and organic) via carboxyl reactions and more.
Catalog no | Name | MW (Da) | Packsize |
CMD4 | CM-dextran 4 | 4000 | 10g |
CMD4 | CM-dextran 4 | 4000 | 100g |
CMD10 | CM-dextran 10 | 10000 | 10g |
CMD10 | CM-dextran 10 | 10000 | 100g |
CMD20 | CM-dextran 20 | 20000 | 10g |
CMD20 | CM-dextran 20 | 20000 | 100g |
CMD40 | CM-dextran 40 | 40000 | 10g |
CMD40 | CM-dextran 40 | 40000 | 100g |
CMD70 | CM-dextran 70 | 70000 | 10g |
CMD70 | CM-dextran 70 | 70000 | 100g |
CMD150 | CM-dextran 150 | 150000 | 10g |
CMD150 | CM-dextran 150 | 150000 | 100g |
CMD500 | CM-dextran 500 | 500000 | 10g |
CMD500 | CM-dextran 500 | 500000 | 100g |
References
Click to view publications
- Li, B. et al. Functionalized polymer microbubbles as new molecular ultrasound contrast agent to target P-selectin in thrombus. Biomaterials 194, 139–150 (2019).
- Hwang, H. et al. MESIA: Magnetic force-assisted electrochemical sandwich immunoassays for quantification of prostate-specific antigen in human serum. Analytica Chimica Acta 1061, 92–100 (2019).
- Juenet, M. et al. Thrombolytic therapy based on fucoidan-functionalized polymer nanoparticles targeting P-selectin. Biomaterials 156, 204–216 (2018).
- Ficko, B. W., NDong, C., Giacometti, P., Griswold, K. E. & Diamond, S. G. A Feasibility Study of Nonlinear Spectroscopic Measurement of Magnetic Nanoparticles Targeted to Cancer Cells. IEEE Transactions on Biomedical Engineering 64, 972–979 (2017).
- Burke, M. et al. Regulation of Scaffold Cell Adhesion Using Artificial Membrane Binding Proteins. Macromolecular Bioscience 17, 1600523 (2017).
- Terentyeva, T. G. et al. Bioactive flake–shell capsules: soft silica nanoparticles for efficient enzyme immobilization. J. Mater. Chem. B 1, 3248–3256 (2013).
- Asgeirsson, D., Venturoli, D., Rippe, B. & Rippe, C. Increased glomerular permeability to negatively charged Ficoll relative to neutral Ficoll in rats. American Journal of Physiology-Renal Physiology 291, F1083–F1089 (2006).