TDB–Antonia Red™ Dextrans

TDB–Antonia Red™ Dextrans

CAS number: not available

Antonia Red™-dextran is supplied as a purple powder that is readily soluble in water

or electrolyte solutions. They are primarily used for studying permeability and

transport in cells and tissues, cell lineage tracing and vasculature studies.

Spectral data: Excitation is best performed at 583 nm and fluorescence

measured at 602 nm

Fluorescent derivatives

Antonia Red™ Dextrans

Antonia Red™ is a red-shifted dye with an absorbance maximum at 583 and an emission wavelength of 602 nm. All batches are carefully controlled for molecular weight, appearance, solubility, degree of substitution, fluorescence and free dye. TdB Labs produce Antonia Red-dextran from 4 kDa to 150 kDa. Antonia Red-dextrans are supplied as a purple powder.

Can’t find what you are looking for? We can always produce a customised product for you. Read more here.

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Structure
Antonia Red™-dextran are synthesised from well-characterised dextran fractions derived from Leuconostoc mesenteroides. The dextran fractions are then labelled with Antonia Red. The degree of substitution lies between 0.001-0.01.

Spectral data
Antonia Red™-dextran has an absorbance maximum at 583 nm and an emission wavelength of 602 nm in borate buffer at pH 9.0.

Storage and stability
Antonia Red™ dextran is stable for more than 6 years when stored dry in well-sealed containers at ambient temperature

Solubility
Antonia Red™-dextran dissolves readily in water.

Application
Antonia Red™-dextran is mainly used for studying permeability and microcirculation. It can also be used as a molecular size marker, for studies of drug delivery and more. Antonia Red shows bright fluorescence, has good photo- and chemical stability and is non-pH dependent. Read more about applications here.

Catalog no Name MW (Da) Packsize
ARD4 Antonia RedTM-dextran 4 4000 10mg
ARD4 Antonia RedTM-dextran 4 4000 50mg
ARD20 Antonia RedTM-dextran 20 20000 10mg
ARD20 Antonia RedM-dextran 20 20000 50mg
ARD40 Antonia RedTM-dextran 40 40000 10mg
ARD40 Antonia RedTM-dextran 40 40000 50mg
ARD150. Antonia RedTM-dextran 1 50 150000 10mg
ARD150 Antonia RedTM-dextran 150 150000 50mg

References

Gustafsson, S. et al. Blood-brain barrier integrity in a mouse model of Alzheimer’s disease with or without acute 3D6 immunotherapy. Neuropharmacology 143, 1–9 (2018).

Technical documents

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