Hyaluronic acid (HA) can be obtained from various sources, for example rooster combs or Streptococcus equi. We can supply derivatives of either of these qualities labelled with fluorescein (F-HA). All batches are checked for molecular weight, degree of substitution, loss on drying and free FITC. TdB Labs can produce F-HA with a molecular weight of approximately 1.5 MDa. F-HA is supplied as a yellow powder.

Can’t find what you are looking for? We can always produce a customised product for you. Read more here.

If you need larger quantities, please contact us for a bulk quotation.

Structure
Hyaluronic acid is a polysaccharide composed of alternating β(1-3) glucuronide and β(1-4) glucosaminide units derived from Streptococcus equi. The hyaluronic acid is labelled with 5-amino-fluorescein. The degree of substitution lies between 0.001 and 0.008. The labelling procedure does not lead to depolymerisation of the HA.

Spectral data
F-HA has an excitation maximum at 495 nm and an emission maximum at 524 nm.

Storage and stability
F-HA is stable for more than 6 years when stored dry in well-sealed containers.

Solubility
F-HA dissolves readily in water.

Application
F-HA have been used to e.g. study the hyaluronan uptake in siloxane-hydrogel contact lenses. Read more about applications here.

References

Have you cited this product in a publication? Let us know so we can reference it.