Molecular Dimensions MD1-13 3D Structure Screen 48 x 10 mL

The 3D Structure Screen is formulated for growing protein crystals in the metastable zone using the vapour diffusion technique.

This method is presented in the 3D Structure Screen as an optimized sparse matrix crystal growth screen which allows the 24 “nucleation” conditions of the Mini Screen and 24 “backed-off” conditions for crystal growth to be tried. Formatted for HT blocks as the Heavy + Light (3D Structure Screen) Twin Pack HT-96.

Features of 3D Structure Screen:

Separate nucleation from crystal growth.
A simple method for growing crystals in the metastable zone.
Obtain much larger and better diffracting crystals compared to conventional methods.
This product is manufactured under an exclusive licence from Imperial College of Science, Technology and Medicine, London U.K.

3D Structure Screen 专为使用蒸汽扩散技术在亚稳态区域中生长蛋白质晶体而设计。

这种方法在 3D 结构屏幕中显示为优化的稀疏矩阵晶体生长屏幕，它允许尝试使用 Mini Screen 的 24 个“成核”条件和 24 个“回退”条件进行晶体生长。 为 HT 块格式化为 Heavy + Light（3D 结构屏幕）Twin Pack HT-96。

3D结构画面的特点：

将成核与晶体生长分开。
在亚稳区中生长晶体的简单方法。
与传统方法相比，获得更大更好的衍射晶体。
本产品是在英国伦敦帝国理工学院的独家许可下生产的。

References:  参考文献
Chayen, N. & Saridakis, E. Protein crystallization for genomics: towards high-throughout optimization techniques. Acta Cryst. D58: 921-927 (2002)
Chayen, N. & Saridakis, E. Improving protein crystal quality by decoupling nucleation and growth in vapor diffusion. Protein Science 9(4): 755-757 (2000)
Charron, C et al. Crystallization and preliminary X-ray diffraction data of the second and archaebacterial-type aspartyl-tRNA synthetase from Thermus thermophilus. Acta Cryst. D57: 1177-1179 (2001)