产品编号

JJJP50-10μg
Recombinant Human BAFF Receptor/TNFRSF13C
10μg

669

JJJP50-100μg
Recombinant Human BAFF Receptor/TNFRSF13C
100μg

3075

JJJP50-500μg
Recombinant Human BAFF Receptor/TNFRSF13C
500μg

5418

JJJP50-1mg
Recombinant Human BAFF Receptor/TNFRSF13C
1mg

–

Species

Gene ID

Accession

Source

Length

MW

Tag

Human

115650

Q96RJ3

E. coli

76aa

7.8kDa

－

About this protein

Name

Recombinant Human BAFF Receptor/TNFRSF13C (Recombinant Human B Cell Activating Factor Receptor; rHuBAFF-R)；重组人B细胞激活因子受体/TNFSF13C

Synonyms

BR3; CD268; TNFRSF13C

Purity

>95% by reduced SDS-PAGE analyses.

Biological Activity

Fully biologically active when compared to standard. The ED50 as determined by its ability to block BAFF induced mouse splenocyte survival is 1.0-5.0μg/ml in the presence of 1.0μg/ml of rHuBAFF.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM PB, pH8.0, 500mM NaCl.

Endotoxin

Less than 1EU/μg of rHuBAFF-R as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

B Cell Activating Factor Receptor (BAFF-R), also named tumor necrosis factor receptor superfamily member 13C, is a member of the TNFR superfamily. It is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF receptor is a type III transmembrane protein containing a single extracellular phenylalanine-rich domain and binds with high specificity to BAFF (TNFSF13B). It enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. BAFF receptor/BAFF signaling plays a critical role in B cell survival and maturation.

Amino Acid Sequence

MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG

包装清单:

产品编号

产品名称

包装

JJJP50-10μg

Recombinant Human BAFF Receptor/TNFRSF13C

10μg

JJJP50-100μg

Recombinant Human BAFF Receptor/TNFRSF13C

100μg

JJJP50-500μg

Recombinant Human BAFF Receptor/TNFRSF13C

500μg

–

说明书

1份

保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。