产品编号

JJP56-10μg
Recombinant Human IL-16, 130a.a.
10μg

1671

JJP56-100μg
Recombinant Human IL-16, 130a.a.
100μg

10650

JJP56-500μg
Recombinant Human IL-16, 130a.a.
500μg

18780

JJP56-1mg
Recombinant Human IL-16, 130a.a.
1mg

–

Species

Gene ID

Accession

Source

Length

MW

Tag

Human

3603

Q14005

E. coli

130aa

13.4kDa

－

About this protein

Name

Recombinant Human IL-16, 130a.a. (Recombinant Human Interleukin-16, 130a.a.; rHuIL-16, 130a.a.)；重组人白细胞介素16，130a.a.

Synonyms

LCF; NIL16; PRIL16; prIL-16

Purity

>95% by SDS-PAGE and HPLC analyses.

Biological Activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CD4+ T Lymphocytes is in a concentration range of 1.0-100ng/ml.

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Formulation

Lyophilized from a 0.2μm filtered concentrated solution in 20mM Tris, 150mM NaCl, pH7.0.

Endotoxin

Less than 1EU/μg of rHuIL-16, 130a.a. as determined by LAL method.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. Stock solutions should be apportioned into working aliquots and stored at ≤-20℃. Further dilutions should be made in appropriate buffered solutions.

Category

Cytokine

Background

Human Interleukin-16 (IL-16) is also called lymphocyte chemoattractant factor (LCF) and it has three isoforms which are cleaved from pre-Interleukin-16. IL-16 is mostly secreted by lymphocytes, epithelial cells, eosinophils, and CD8+ T cells. It has many functions including induction of the IL-2Rα on T cells, suppression of human immunodeficiency virus (HIV) replication, inhibition of T-cell antigen receptor/CD3 mediated T-cell stimulation in mixed lymphocyte reactions and so on. It signals through CD4 receptor. Furthermore, recombinant human IL-16(130a.a.) contains 130 amino acid residues and it shares 85%a.a. sequence identity with murine IL-16.

Amino Acid Sequence

MPDLNSSTDS AASASAASDV SVESTAEATV CTVTLEKMSA GLGFSLEGGK GSLHGDKPLT INRIFKGAAS EQSETVQPGD EILQLGGTAM QGLTRFEAWN IIKALPDGPV TIVIRRKSLQ SKETTAAGDS

包装清单:

产品编号

产品名称

包装

JJP56-10μg

Recombinant Human IL-16, 130a.a.

10μg

JJP56-100μg

Recombinant Human IL-16, 130a.a.

100μg

JJP56-500μg

Recombinant Human IL-16, 130a.a.

500μg

–

说明书

1份

保存条件:
-20℃或更低温度保存，至少一年有效。由于蛋白的每次冻融均会引起部分失活，所以首次配制成相应浓度的储存液后(请根据产品简介中Reconstitution一栏的信息配制储存液)，须分装后-20℃或更低温度冻存，以避免反复冻融。
注意事项:
由于有些塑料管壁对某些蛋白有较强的吸附作用，溶液中的蛋白很容易粘附在管壁上，并且粘附后的蛋白很难与管壁分离。而载体蛋白(Carrier protein，如0.1% BSA等)的主要作用是预先封闭塑料管壁上的蛋白结合位点，使细胞因子或重组蛋白不会粘附于管壁。所以一定要使用产品简介中Reconstitution一栏的信息配制储存液。
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